The following gene names and symbols are associated with antigen Pancreatic and Duodenal Homeobox 1 across different species:

pancreatic and duodenal homeobox 1 (PDX1), pancreatic and duodenal homeobox 1 (pdx1)

Other aliases include:

GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1, PDX1, ipf1

On the protein level the following designations are being used for antigen Pancreatic and Duodenal Homeobox 1:

pancreatic and duodenal homeobox 1 – glucose-sensitive factor – insulin upstream factor 1 – somatostatin transcription factor 1 – pancreatic-duodenal homeobox factor 1 – insulin promoter factor 1, homeodomain transcription factor – homeodomain protein PDX-1 – pancreatic duodenal homeobox gene 1 – pancreas/duodenum homeobox protein 1

Pancreatic and Duodenal Homeobox 1 fulfills a number of functions:

protein binding – sequence-specific DNA binding – specific RNA polymerase II transcription factor activity – transcription activator activity – transcription factor activity

Pancreatic and Duodenal Homeobox 1 is relevant to the following processes:

cell differentiation – endocrine pancreas development – exocrine pancreas development – generation of precursor metabolites and energy – glucose homeostasis – glucose metabolic process – insulin secretion – morphogenesis of embryonic epithelium – multicellular organismal development – negative regulation of cell proliferation – negative regulation of transcription from RNA polymerase II promoter – nitric oxide mediated signal transduction – organ morphogenesis – positive regulation of cell proliferation – positive regulation of transcription from RNA polymerase II promoter

Locations for Pancreatic and Duodenal Homeobox 1:

intracellular part – nucleus

Source: NCBI Entrez Gene, Gene Ontology