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Reactivity

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Rabbit 2

Clonality

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IgG 1

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Antigen Patched

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Patched antibody

Rabbit, Polyclonal, IgG
Patched antibody
Reactivity:Human, Mouse (Murine)
Application:WB, IHC, ELISA
ABIN483993
Ships within 7 to 10 Business Days
150.00 $
50µg

Patched antibody

Rabbit, Polyclonal
Patched antibody
Reactivity:Human
Application:WB, IHC
ABIN459674
Ships within 7 to 10 Business Days
743.71 $
100µg
1
Antigen Profile  
Patched
GENE ID SPECIES
35851 Drosophila melanogaster
252317 Drosophila melanogaster
398215 Xenopus laevis
484137 Canis lupus familiaris
778726 Ciona intestinalis

The following gene names and symbols are associated with antigen Patched across different species:

patched (ptc), patched (patch), patched homolog 1 (ptch1), patched (PTCH1), patched receptor (patched)

Other aliases include:

BcDNA:RH36596, Conf, PTC, Ptc_Dm, Ptch, dPtc, l(2)k02507, pat, rubr, tuf, DmelCG2411, CG2411, ptc1, XPtc1, patched, patched1, PTCH1

On the protein level the following designations are being used for antigen Patched:

patched – CG2411-PA – ptc-PA – confused – tufted – rubberneck – patch – patched homolog 1 – patched-1 – patched receptor

Patched fulfills a number of functions:

hedgehog receptor activity – lipoprotein receptor activity – protein binding – transmembrane receptor activity

Patched is relevant to the following processes:

Bolwig's organ morphogenesis – anterior/posterior lineage restriction, imaginal disc – anterior/posterior pattern formation – axon guidance – blastoderm segmentation – dephosphorylation – determination of genital disc primordium – embryonic pattern specification – eye-antennal disc morphogenesis – germ-line stem cell division – imaginal disc-derived wing morphogenesis – lipid homeostasis – negative regulation of smoothened signaling pathway – oogenesis – ovarian follicle cell development – peripheral nervous system development – proteolysis – regulation of mitotic cell cycle – regulation of protein import into nucleus – smoothened signaling pathway – somatic stem cell division – wing disc anterior/posterior pattern formation

Locations for Patched:

cytoplasm – endocytic vesicle – fusome – integral to membrane – integral to plasma membrane – perinuclear region of cytoplasm – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology