The following gene names and symbols are associated with antigen Platelet Factor 4 across different species:

platelet factor 4 (PF4), platelet factor 4 (Pf4)

Other aliases include:

CXCL4, SCYB4, MGC138298, Cxcl4, Scyb4, PF-4, Pf4a, RATPF4A, PF4

On the protein level the following designations are being used for antigen Platelet Factor 4:

platelet factor 4 (chemokine (C-X-C motif) ligand 4) – chemokine (C-X-C motif) ligand 4 – platelet factor 4 – C-X-C motif chemokine 4

Platelet Factor 4 fulfills a number of functions:

chemokine activity – heparin binding – cytokine activity – molecular_function

Platelet Factor 4 is relevant to the following processes:

G-protein coupled receptor protein signaling pathway – chemotaxis – cytokine-mediated signaling pathway – immune response – leukocyte chemotaxis – negative regulation of MHC class II biosynthetic process – negative regulation of angiogenesis – negative regulation of apoptosis – negative regulation of cytolysis – negative regulation of megakaryocyte differentiation – platelet activation – positive regulation of gene expression – positive regulation of macrophage derived foam cell differentiation – positive regulation of tumor necrosis factor production – positive regulation of macrophage differentiation – protein complex assembly

Locations for Platelet Factor 4:

extracellular region – extracellular space – platelet alpha granule lumen – platelet alpha granule – protein complex – vesicle

Source: NCBI Entrez Gene, Gene Ontology