The following gene names and symbols are associated with antigen Proprotein Convertase Subtilisin/kexin Type 6 across different species:

proprotein convertase subtilisin/kexin type 6 (PCSK6), proprotein convertase subtilisin/kexin type 6 (Pcsk6), proprotein convertase subtilisin/kexin type 6 (EAMY_2296), proprotein convertase subtilisin/kexin type 6 (pcsk6)

Other aliases include:

SPC4, PACE4, Spc4, Pace4, PCSK6

On the protein level the following designations are being used for antigen Proprotein Convertase Subtilisin/kexin Type 6:

paired basic amino acid cleaving system 4 – subtilisin-like protease – subtilisin/kexin-like protease PACE4 – subtilisin-like proprotein convertase 4 – proprotein convertase subtilisin/kexin type 6 – kexin-like protease PC7A – Subtilisin - like endoprotease – paired basic amino acid cleaving enzyme 4 – proprotein convertase PACE4 – proprotein convertase subtilisin/kexin type 6-like

Proprotein Convertase Subtilisin/kexin Type 6 fulfills a number of functions:

calcium ion binding – eukaryotic cell surface binding – heparin binding – nerve growth factor binding – peptidase activity – serine-type endopeptidase activity – endopeptidase activity – zinc ion binding

Proprotein Convertase Subtilisin/kexin Type 6 is relevant to the following processes:

glycoprotein metabolic process – nerve growth factor processing – nerve growth factor production – proteolysis – regulation of BMP signaling pathway – secretion by cell – determination of left/right symmetry – peptide hormone processing – protein maturation by peptide bond cleavage – zygotic determination of anterior/posterior axis, embryo

Locations for Proprotein Convertase Subtilisin/kexin Type 6:

Golgi lumen – cell surface – endoplasmic reticulum – extracellular matrix – extracellular region – extracellular space – extrinsic to membrane – membrane – soluble fraction – intracellular

Source: NCBI Entrez Gene, Gene Ontology