The following gene names and symbols are associated with antigen Protein Kinase, DNA-Activated, Catalytic Polypeptide across different species:

protein kinase, DNA-activated, catalytic polypeptide (PRKDC), protein kinase, DNA-activated, catalytic polypeptide (prkdc-A), protein kinase, DNA-activated, catalytic polypeptide (LOC100224961)

Other aliases include:

HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, prkdc-A, dna-pkcs, PRKDC, DNA-PKCS

On the protein level the following designations are being used for antigen Protein Kinase, DNA-Activated, Catalytic Polypeptide:

protein kinase, DNA-activated, catalytic polypeptide – hyper-radiosensitivity of murine scid mutation, complementing 1 – DNA-dependent protein kinase catalytic subunit – protein kinase catalytic subunit (DNA-dependent protein kinase) – DNA-activated protein kinase catalytic polypeptide – DNA-dependent protein kinase catalytic subunit-like

Protein Kinase, DNA-Activated, Catalytic Polypeptide fulfills a number of functions:

ATP binding – DNA binding – DNA-dependent protein kinase activity – nucleotide binding – protein binding – transferase activity – kinase activity – phosphotransferase activity, alcohol group as acceptor

Protein Kinase, DNA-Activated, Catalytic Polypeptide is relevant to the following processes:

DNA recombination – DNA repair – double-strand break repair via nonhomologous end joining – peptidyl-serine phosphorylation – protein modification process – response to DNA damage stimulus – B cell lineage commitment – T cell differentiation in the thymus – T cell lineage commitment – T cell receptor V(D)J recombination – brain development – germ cell programmed cell death – heart development – immunoglobulin V(D)J recombination – lymphocyte differentiation – positive regulation of apoptosis – pro-B cell differentiation – protein destabilization – response to gamma radiation – somitogenesis – telomere maintenance

Locations for Protein Kinase, DNA-Activated, Catalytic Polypeptide:

DNA-dependent protein kinase-DNA ligase 4 complex – nucleoplasm – nucleus

Source: NCBI Entrez Gene, Gene Ontology