The following gene names and symbols are associated with antigen S-Phase Kinase-Associated Protein 2 across different species:

S-phase kinase-associated protein 2 (p45) (SKP2), S-phase kinase-associated protein 2 (p45) (Skp2)

Other aliases include:

FBL1, FLB1, FBXL1, MGC1366, MGC102075, MGC116668, RGD1562456, SKP2, MGC152600

On the protein level the following designations are being used for antigen S-Phase Kinase-Associated Protein 2:

S-phase kinase-associated protein 2 – CDK2/cyclin A-associated protein p45 – p45 – FWD1 – F-box protein Skp2 – F-box/WD-40 protein 1 – cyclin A/CDK2-associated protein p45 – cyclin-A/CDK2-associated protein p45

S-Phase Kinase-Associated Protein 2 fulfills a number of functions:

protein binding – kinase activity – ubiquitin-protein ligase activity

S-Phase Kinase-Associated Protein 2 is relevant to the following processes:

G1/S transition of mitotic cell cycle – cell proliferation – negative regulation of survival gene product expression – regulation of cell cycle – ubiquitin-dependent protein catabolic process – positive regulation of estrogen receptor signaling pathway – positive regulation of smooth muscle cell proliferation – protein polyubiquitination – cellular response to cell-matrix adhesion

Locations for S-Phase Kinase-Associated Protein 2:

SCF ubiquitin ligase complex

Source: NCBI Entrez Gene, Gene Ontology