The following gene names and symbols are associated with antigen SMAD, Mothers Against DPP Homolog 4 across different species:

SMAD family member 4 (SMAD4)

Other aliases include:

JIP, DPC4, MADH4, SMAD4

On the protein level the following designations are being used for antigen SMAD, Mothers Against DPP Homolog 4:

mothers against decapentaplegic homolog 4 – OTTHUMP00000163548 – SMAD, mothers against DPP homolog 4 – deleted in pancreatic carcinoma locus 4 – MAD, mothers against decapentaplegic homolog 4 – mothers against decapentaplegic, Drosophila, homolog of, 4 – SMAD family member 4 – mothers against decapentaplegic-like 4

SMAD, Mothers Against DPP Homolog 4 fulfills a number of functions:

R-SMAD binding – collagen binding – promoter binding – protein homodimerization activity – transcription activator activity – transcription factor activity – transforming growth factor beta receptor, common-partner cytoplasmic mediator activity

SMAD, Mothers Against DPP Homolog 4 is relevant to the following processes:

BMP signaling pathway – SMAD protein complex assembly – SMAD protein signal transduction – anterior/posterior pattern formation – branching involved in ureteric bud morphogenesis – gastrulation with mouth forming second – kidney development – negative regulation of cell growth – negative regulation of cell proliferation – negative regulation of transcription, DNA-dependent – neuron fate commitment – palate development – positive regulation of SMAD protein nuclear translocation – positive regulation of epithelial to mesenchymal transition – positive regulation of pathway-restricted SMAD protein phosphorylation – positive regulation of transcription from RNA polymerase II promoter – regulation of binding – regulation of transforming growth factor beta receptor signaling pathway – regulation of transforming growth factor-beta2 production – response to hypoxia

Locations for SMAD, Mothers Against DPP Homolog 4:

activin responsive factor complex – cytoplasm – cytosol – intracellular – nucleoplasm – nucleus

Source: NCBI Entrez Gene, Gene Ontology