The following gene names and symbols are associated with antigen SRY (Sex Determining Region Y)-Box 2 across different species:

SRY (sex determining region Y)-box 2 (SOX2), SRY (sex determining region Y)-box 2 (Sox2), SRY (sex determining region Y)-box 2 (LOC100231711), SRY-box containing gene 2 (Sox2)

Other aliases include:

ANOP3, MCOPS3, MGC2413, RGD1565646, SOX2, MGC148683, lcc, ysb, Sox-2

On the protein level the following designations are being used for antigen SRY (Sex Determining Region Y)-Box 2:

sex-determining region Y-box 2 – transcription factor SOX2 – SRY-related HMG-box gene 2 – SRY (sex determining region Y)-box 2 – SRY-box containing gene 2 – SRY-box 2 – SRY-related HMG-box 2 – sex determining region Y-box 2 – transcription factor SOX-2 – OTTMUSP00000023485

SRY (Sex Determining Region Y)-Box 2 fulfills a number of functions:

chromatin binding – protein binding – sequence-specific DNA binding – transcription factor activity – DNA binding – miRNA binding – molecular_function – promoter binding – sequence-specific DNA binding transcription factor activity

SRY (Sex Determining Region Y)-Box 2 is relevant to the following processes:

adenohypophysis development – anatomical structure formation involved in morphogenesis – cell fate specification – cerebral cortex development – chromatin organization – detection of mechanical stimulus involved in equilibrioception – detection of mechanical stimulus involved in sensory perception of sound – diencephalon morphogenesis – embryonic organ development – forebrain neuron differentiation – inner ear morphogenesis – lens induction in camera-type eye – male genitalia development – negative regulation of Wnt receptor signaling pathway – negative regulation of neuron differentiation – negative regulation of osteoblast differentiation – negative regulation of transcription from RNA polymerase II promoter – neuron fate commitment – olfactory placode formation – pigment biosynthetic process – positive regulation of Notch signaling pathway – positive regulation of neuroblast proliferation – positive regulation of neuron differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to chemical stimulus – response to retinoic acid – retina morphogenesis in camera-type eye – stem cell maintenance – tongue development – biological_process – cell cycle arrest – cell fate commitment – epithelial tube branching involved in lung morphogenesis – eye development – forebrain development – inner ear development – lung alveolus development – negative regulation of canonical Wnt receptor signaling pathway – negative regulation of cell differentiation – negative regulation of epithelial cell proliferation – osteoblast differentiation – pituitary gland development – positive regulation of MAPKKK cascade – positive regulation of epithelial cell differentiation – positive regulation of transcription – regulation of caspase activity – regulation of gene expression – response to growth factor stimulus – response to wounding – sensory perception of sound – somatic stem cell maintenance – regulation of transcription – transcription

Locations for SRY (Sex Determining Region Y)-Box 2:

cytoplasm – nucleus – transcription factor complex – cellular_component – cytosol

Source: NCBI Entrez Gene, Gene Ontology