The following gene names and symbols are associated with antigen Second Mitochondria-Derived Activator of Caspase across different species:

diablo homolog (Drosophila) (DIABLO), diablo homolog (diablo), Smac protein precursor (smac)

Other aliases include:

SMAC, SMAC3, DIABLO-S, FLJ10537, FLJ25049, smac, smac3, diablo-s, XSmac, diablo

On the protein level the following designations are being used for antigen Second Mitochondria-Derived Activator of Caspase:

diablo – 0610041G12Rik – mitochondrial Smac protein – direct IAP-binding protein with low pI – second mitochondria-derived activator of caspase – diablo homolog – Diablo homolog, mitochondrial – Direct IAP-binding protein with low pI – Second mitochondria-derived activator of caspase – Smac protein precursor

Second Mitochondria-Derived Activator of Caspase fulfills a number of functions:

protein binding

Second Mitochondria-Derived Activator of Caspase is relevant to the following processes:

activation of caspase activity by cytochrome c – induction of apoptosis – induction of apoptosis via death domain receptors

Locations for Second Mitochondria-Derived Activator of Caspase:

cytosol – mitochondrion

Source: NCBI Entrez Gene, Gene Ontology