The following gene names and symbols are associated with antigen Single Ig IL-1R-Related Molecule across different species:

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR)

Other aliases include:

TIR8, MGC110992

On the protein level the following designations are being used for antigen Single Ig IL-1R-Related Molecule:

single Ig IL-1R-related molecule – single immunoglobulin domain IL1R1 related

Single Ig IL-1R-Related Molecule fulfills a number of functions:

protein binding – transmembrane receptor activity

Single Ig IL-1R-Related Molecule is relevant to the following processes:

acute-phase response – innate immune response – negative regulation of chemokine biosynthetic process – negative regulation of cytokine-mediated signaling pathway – negative regulation of lipopolysaccharide-mediated signaling pathway – negative regulation of transcription factor activity – signal transduction

Locations for Single Ig IL-1R-Related Molecule:

integral to membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology