The following gene names and symbols are associated with antigen Smoothened across different species:

smoothened (smo), smoothened (Smo), smoothened (SMO)

Other aliases include:

SMO, dSmo, DmelCG11561, CG11561, Smo, GB10379

On the protein level the following designations are being used for antigen Smoothened:

smoothened – CG11561-PA – smo-PA – smooth

Smoothened fulfills a number of functions:

G-protein coupled receptor activity – hedgehog receptor activity – non-G-protein coupled 7TM receptor activity – protein binding – transmembrane receptor activity

Smoothened is relevant to the following processes:

Bolwig's organ morphogenesis – Wnt receptor signaling pathway – anterior/posterior lineage restriction, imaginal disc – blastoderm segmentation – eye morphogenesis – eye-antennal disc morphogenesis – negative regulation of S phase of mitotic cell cycle – ovarian follicle cell development – regulation of mitotic cell cycle – signal transduction – smoothened signaling pathway – somatic stem cell maintenance – wing disc anterior/posterior pattern formation

Locations for Smoothened:

endosome – integral to membrane – membrane – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology