The following gene names and symbols are associated with antigen TANK-Binding Kinase 1 across different species:

TANK-binding kinase 1 (TBK1), TANK-binding kinase 1 (Tbk1), TANK-binding kinase 1 (tbk1), TANK-binding kinase 1 (LOC100358771)

Other aliases include:

NAK, T2K, FLJ11330, AI462036, AW048562, MGC150301, MGC150302, 1200008B05Rik, tbk1, MGC81514, TBK1, wu:fk70c05, zgc:136548, nak, t2k

On the protein level the following designations are being used for antigen TANK-Binding Kinase 1:

TANK-binding kinase 1 – NF-kB-activating kinase – serine/threonine-protein kinase TBK1 – T2K – serine/threonine protein kinase TBK1 – TANK binding kinase 1 – NF-kappa-B-activating kinase – serine/threonine-protein kinase TBK1-like

TANK-Binding Kinase 1 fulfills a number of functions:

ATP binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein kinase activity – phosphoprotein binding

TANK-Binding Kinase 1 is relevant to the following processes:

innate immune response – interspecies interaction between organisms – positive regulation of I-kappaB kinase/NF-kappaB cascade – protein amino acid phosphorylation – response to virus – activation of innate immune response – defense response to Gram-positive bacterium – negative regulation of gene expression – positive regulation of interferon-beta biosynthetic process – I-kappaB kinase/NF-kappaB cascade

Locations for TANK-Binding Kinase 1:

cytoplasm – cytosol – endosome membrane – cellular_component

Source: NCBI Entrez Gene, Gene Ontology