The following gene names and symbols are associated with antigen Toll-Like Receptor 4 across different species:

toll-like receptor 4 (TLR4), toll-like receptor 4 (Tlr4)

Other aliases include:

TOLL, CD284, hToll, ARMD10, Lps, Ly87, Ran/M1, Rasl2-8

On the protein level the following designations are being used for antigen Toll-Like Receptor 4:

toll-like receptor 4 – homolog of Drosophila toll – OTTMUSP00000000296 – lipopolysaccharide response

Toll-Like Receptor 4 fulfills a number of functions:

lipopolysaccharide receptor activity – protein binding – transmembrane receptor activity – receptor activity

Toll-Like Receptor 4 is relevant to the following processes:

I-kappaB kinase/NF-kappaB cascade – T-helper 1 type immune response – defense response to Gram-negative bacterium – detection of fungus – detection of lipopolysaccharide – inflammatory response – innate immune response – macrophage activation – negative regulation of osteoclast differentiation – positive regulation of interleukin-12 biosynthetic process – positive regulation of interleukin-8 biosynthetic process – positive regulation of platelet activation – positive regulation of tumor necrosis factor biosynthetic process – signal transduction – activation of innate immune response – immune response – interferon-gamma production – positive regulation of B cell proliferation – positive regulation of ERK1 and ERK2 cascade – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of JNK cascade – positive regulation of MHC class II biosynthetic process – positive regulation of NF-kappaB transcription factor activity – positive regulation of interferon-beta biosynthetic process – positive regulation of interleukin-6 production – positive regulation of lymphocyte proliferation – positive regulation of macrophage cytokine production – positive regulation of nitric oxide biosynthetic process – positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway – positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway – positive regulation of stress-activated MAPK cascade – positive regulation of tumor necrosis factor production – production of nitric oxide during acute inflammatory response – response to bacterium – response to lipopolysaccharide – response to lipoteichoic acid – defense response to bacterium

Locations for Toll-Like Receptor 4:

external side of plasma membrane – integral to plasma membrane – lipopolysaccharide receptor complex – perinuclear region of cytoplasm – plasma membrane – integral to membrane – intrinsic to membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology

17 products cited in Circulation research anti-Toll-Like Receptor 2 (TLR2) antibody (ABIN158484) , anti-Toll-Like Receptor 2 (TLR2) antibody (ABIN158485) , anti-Toll-Like Receptor 2 (TLR2) antibody (Biotin) (ABIN158487) , anti-Toll-Like Receptor 2 (TLR2) antibody (FITC) (ABIN158488) , anti-Toll-Like Receptor 2 (TLR2) antibody (FITC) (ABIN158489) , among others.

6 products cited in Journal of immunology (Baltimore, Md. : 1950) anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN158700) , anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN158701) , anti-Toll-Like Receptor 4 (TLR4) antibody (Biotin) (ABIN158703) , anti-Toll-Like Receptor 4 (TLR4) antibody (PE) (ABIN158704) , anti-Toll-Like Receptor 4 (TLR4) antibody (PE) (ABIN158705) , among others.

6 products cited in Hybridoma and hybridomics anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN158700) , anti-Toll-Like Receptor 4 (TLR4) antibody (ABIN158701) , anti-Toll-Like Receptor 4 (TLR4) antibody (Biotin) (ABIN158703) , anti-Toll-Like Receptor 4 (TLR4) antibody (PE) (ABIN158704) , anti-Toll-Like Receptor 4 (TLR4) antibody (PE) (ABIN158705) , among others.

13 products cited in Journal of immunology (Baltimore, Md. : 1950) anti-Toll-Like Receptor 4 (TLR4) (MD2 Complex) antibody (ABIN156926) , anti-Toll-Like Receptor 4 (TLR4) (MD2 Complex) antibody (ABIN156927) , anti-Toll-Like Receptor 4 (TLR4) (MD2 Complex) antibody (Biotin) (ABIN156928) , anti-Toll-Like Receptor 4 (TLR4) (MD2 Complex) antibody (PE) (ABIN156930) , anti-Toll-Like Receptor 4 (TLR4) (MD2 Complex) antibody (PE) (ABIN156931) , among others.

17 products cited in Infection and immunity anti-Toll-Like Receptor 2 (TLR2) antibody (ABIN158484) , anti-Toll-Like Receptor 2 (TLR2) antibody (ABIN158485) , anti-Toll-Like Receptor 2 (TLR2) antibody (Biotin) (ABIN158487) , anti-Toll-Like Receptor 2 (TLR2) antibody (FITC) (ABIN158488) , anti-Toll-Like Receptor 2 (TLR2) antibody (FITC) (ABIN158489) , among others.

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