The following gene names and symbols are associated with antigen Toll-Like Receptor 7 across different species:

toll-like receptor 7 (TLR7), toll-like receptor 7 (Tlr7), toll-like receptor 7 (tlr7)

Other aliases include:

RGD1563357, TLR7A

On the protein level the following designations are being used for antigen Toll-Like Receptor 7:

toll-like receptor 7 – OTTMUSP00000021129 – OTTMUSP00000021133 – toll like receptor 7 – toll-like receptor 7-long

Toll-Like Receptor 7 fulfills a number of functions:

double-stranded RNA binding – protein binding – siRNA binding – single-stranded RNA binding – transmembrane receptor activity – receptor activity – drug binding

Toll-Like Receptor 7 is relevant to the following processes:

I-kappaB kinase/NF-kappaB cascade – defense response to virus – inflammatory response – innate immune response – positive regulation of interferon-alpha biosynthetic process – positive regulation of interferon-beta biosynthetic process – positive regulation of interferon-gamma biosynthetic process – positive regulation of interleukin-6 production – positive regulation of interleukin-8 biosynthetic process – signal transduction – immune response – I-kappaB phosphorylation – microglial cell activation involved in immune response – pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity – positive regulation of NF-kappaB import into nucleus – positive regulation of chemokine production – positive regulation of interleukin-8 production – response to chemical stimulus – toll-like receptor 7 signaling pathway – toll-like receptor signaling pathway – positive regulation of interleukin-1 biosynthetic process – positive regulation of interleukin-6 biosynthetic process – regulation of defense response to virus by host

Locations for Toll-Like Receptor 7:

endosome membrane – integral to membrane – membrane – intrinsic to membrane – cytoplasm – early phagosome – endoplasmic reticulum – endosome – lysosome – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology