The following gene names and symbols are associated with antigen Toll-Like Receptor 8 across different species:

toll-like receptor 8 (TLR8), toll-like receptor 8 (Tlr8)

Other aliases include:

CD288, MGC119599, MGC119600

On the protein level the following designations are being used for antigen Toll-Like Receptor 8:

toll-like receptor 8 – OTTMUSP00000021127

Toll-Like Receptor 8 fulfills a number of functions:

DNA binding – Toll binding – double-stranded RNA binding – protein binding – single-stranded RNA binding – transmembrane receptor activity – receptor activity

Toll-Like Receptor 8 is relevant to the following processes:

I-kappaB kinase/NF-kappaB cascade – defense response to virus – detection of virus – immunoglobulin mediated immune response – inflammatory response – positive regulation of innate immune response – positive regulation of interferon-alpha biosynthetic process – positive regulation of interferon-beta biosynthetic process – positive regulation of interferon-gamma biosynthetic process – positive regulation of interleukin-8 biosynthetic process – signal transduction – immune response – innate immune response

Locations for Toll-Like Receptor 8:

endosome membrane – integral to membrane – membrane – intrinsic to membrane

Source: NCBI Entrez Gene, Gene Ontology