The following gene names and symbols are associated with antigen Topoisomerase (DNA) I across different species:

topoisomerase (DNA) I (TOP1), topoisomerase (DNA) I (Top1), Topoisomerase 1 (Top1), DNA topoisomerase I (top1), DNA topoisomerase I (topA), DNA topoisomerase I (ZMO1193), DNA topoisomerase I (Mrad2831_6322), DNA topoisomerase I (Lferr_0016), DNA topoisomerase I (PC1_2015), DNA topoisomerase I (Za10_0136), DNA topoisomerase I (Gbro_0575), DNA topoisomerase I (Dd586_2108), DNA topoisomerase I (Kvar_3044), DNA topoisomerase I (Alvin_2069), DNA topoisomerase I (Dacet_0849), DNA topoisomerase I (Mrub_1615), DNA topoisomerase I (Arnit_2962), DNA topoisomerase I (Ndas_4953), DNA topoisomerase I (Trad_2377), DNA topoisomerase I (Acear_1653), DNA topoisomerase I (Mahau_0844), DNA topoisomerase I (Mesop_4109), DNA topoisomerase I (Thein_1586), DNA topoisomerase I (Theth_0241)

Other aliases include:

TOPI, Top-1, AI467334, D130064I21Rik, TOP1, TopI, Topo I, TopoI, dTopoI, l(1)G0134, l(1)G0201, l(1)G0229, l(1)G0278, l(1)top1, DmelCG6146, CG6146, Ab2-086

On the protein level the following designations are being used for antigen Topoisomerase (DNA) I:

DNA topoisomerase I – type I DNA topoisomerase – DNA topoisomerase 1 – OTTMUSP00000001137 – topoisomerase 1, isoform A – CG6146-PA – Top1-PA – topoisomerase1 – topoisomerase I – type I topoisomerase – topoisomerase 1, isoform C – CG6146-PC – Top1-PC – topoisomerase 1, isoform B – CG6146-PB – Top1-PB

Topoisomerase (DNA) I fulfills a number of functions:

ATP binding – DNA topoisomerase (ATP-hydrolyzing) activity – DNA topoisomerase type I activity – chromatin binding – nucleotide binding – protein binding – DNA binding – DNA topoisomerase activity – chromatin DNA binding – isomerase activity – protein complex binding

Topoisomerase (DNA) I is relevant to the following processes:

DNA replication – DNA topological change – DNA unwinding during replication – embryonic cleavage – interspecies interaction between organisms – phosphorylation – programmed cell death – response to drug – rRNA transcription – cell proliferation – chromosome condensation – chromosome segregation – embryonic development – instar larval development – multicellular organismal development – oogenesis – DNA unwinding involved in replication – cellular response to luteinizing hormone stimulus – cellular response to stress – organ regeneration – response to cAMP – response to temperature stimulus – chromatin assembly or disassembly – chromatin organization – mitotic chromosome condensation – transcription of nuclear rRNA large RNA polymerase I transcript

Locations for Topoisomerase (DNA) I:

chromosome – cytoplasm – nucleolus – nucleoplasm – nucleus – perikaryon – DNA-directed RNA polymerase II, core complex – polytene chromosome puff – dense fibrillar component – nuclear chromosome – nuclear chromatin

Source: NCBI Entrez Gene, Gene Ontology