The following gene names and symbols are associated with antigen Topoisomerase (DNA) II beta 180kDa across different species:

topoisomerase (DNA) II beta 180kDa (TOP2B)

Other aliases include:

TOPIIB, top2beta, TOP2B

On the protein level the following designations are being used for antigen Topoisomerase (DNA) II beta 180kDa:

DNA topoisomerase II, beta isozyme – topo II beta – antigen MLAA-44 – topoisomerase IIb – topoisomerase II beta – U937 associated antigen – DNA topoisomerase II beta – DNA topoisomerase II, 180 kD – topoisomerase (DNA) II beta 180kDa

Topoisomerase (DNA) II beta 180kDa fulfills a number of functions:

ATP binding – DNA topoisomerase (ATP-hydrolyzing) activity – chromatin binding – histone deacetylase binding – nucleotide binding – protein C-terminus binding – protein heterodimerization activity – protein kinase C binding

Topoisomerase (DNA) II beta 180kDa is relevant to the following processes:

DNA topological change – axonogenesis – forebrain development – neuron migration

Locations for Topoisomerase (DNA) II beta 180kDa:

chromosome – cytoplasm – cytosol – heterochromatin – nucleolus – nucleoplasm – nucleus

Source: NCBI Entrez Gene, Gene Ontology