The following gene names and symbols are associated with antigen Transforming Growth Factor beta Receptor I across different species:

transforming growth factor, beta receptor 1 (TGFBR1)

Other aliases include:

AAT5, ALK5, SKR4, ALK-5, LDS1A, LDS2A, TGFR-1, ACVRLK4

On the protein level the following designations are being used for antigen Transforming Growth Factor beta Receptor I:

transforming growth factor, beta receptor I – activin receptor-like kinase 5 – transforming growth factor beta receptor I – serine/threonine-protein kinase receptor R4 – activin A receptor type II-like kinase, 53kD – activin A receptor type II-like kinase, 53kDa – transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)

Transforming Growth Factor beta Receptor I fulfills a number of functions:

ATP binding – SMAD binding – magnesium ion binding – manganese ion binding – nucleotide binding – protein heterodimerization activity – protein serine/threonine kinase activity – receptor activity – transferase activity – transforming growth factor beta binding – transforming growth factor beta receptor activity, type I – type II transforming growth factor beta receptor binding

Transforming Growth Factor beta Receptor I is relevant to the following processes:

activation of MAPKK activity – anterior/posterior pattern formation – artery morphogenesis – cell motility – collagen fibril organization – embryonic cranial skeleton morphogenesis – germ cell migration – heart development – in utero embryonic development – kidney development – neuron fate commitment – palate development – parathyroid gland development – peptidyl-serine phosphorylation – peptidyl-threonine phosphorylation – pharyngeal system development – positive regulation of SMAD protein nuclear translocation – positive regulation of cell growth – positive regulation of cell motion – positive regulation of cell proliferation – positive regulation of pathway-restricted SMAD protein phosphorylation – positive regulation of protein kinase B signaling cascade – positive regulation of survival gene product expression – positive regulation of transcription – response to cholesterol – signal transduction – skeletal system morphogenesis – thymus development – transforming growth factor beta receptor signaling pathway

Locations for Transforming Growth Factor beta Receptor I:

integral to membrane – transforming growth factor beta receptor complex

Source: NCBI Entrez Gene, Gene Ontology