The following gene names and symbols are associated with antigen Tumor Necrosis Factor Receptor Superfamily, Member 10a across different species:

tumor necrosis factor receptor superfamily, member 10a (TNFRSF10A)

Other aliases include:

DR4, APO2, CD261, MGC9365, TRAILR1, TRAILR-1, TNFRSF10A

On the protein level the following designations are being used for antigen Tumor Necrosis Factor Receptor Superfamily, Member 10a:

tumor necrosis factor receptor superfamily, member 10a – death receptor 4 – cytotoxic TRAIL receptor – TNF-related apoptosis inducing ligand receptor 1 – tumor necrosis factor receptor superfamily member 10A-like

Tumor Necrosis Factor Receptor Superfamily, Member 10a fulfills a number of functions:

TRAIL binding – caspase activator activity – death receptor activity – receptor activity – transcription factor binding

Tumor Necrosis Factor Receptor Superfamily, Member 10a is relevant to the following processes:

activation of NF-kappaB-inducing kinase activity – activation of caspase activity – induction of apoptosis – induction of apoptosis via death domain receptors – signal transduction

Locations for Tumor Necrosis Factor Receptor Superfamily, Member 10a:

integral to membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology