The following gene names and symbols are associated with antigen UACA across different species:

uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)

Other aliases include:

NUCLING, FLJ10128, KIAA1561, MGC141967, MGC141969

On the protein level the following designations are being used for antigen UACA:

uveal autoantigen with coiled-coil domains and ankyrin repeats – nuclear membrane binding protein – uveal autoantigen with coiled coil domains and ankyrin repeats

UACA fulfills a number of functions:

molecular_function – protein binding

UACA is relevant to the following processes:

DNA damage response, signal transduction resulting in induction of apoptosis – induction of apoptosis by oxidative stress – negative regulation of NF-kappaB import into nucleus – negative regulation of inflammatory response – positive regulation of apoptosis – positive regulation of caspase activity – positive regulation of protein import into nucleus – response to UV – viral reproduction

Locations for UACA:

apoptosome – cytoplasm – cytoskeleton – cytosol – extracellular region – membrane fraction – nuclear envelope – nucleus – perinuclear region of cytoplasm – soluble fraction

Source: NCBI Entrez Gene, Gene Ontology