The following gene names and symbols are associated with antigen WD Repeat Domain 5 across different species:

WD repeat domain 5 (WDR5), WD repeat domain 5 (Wdr5), WD repeat domain 5 (wdr5), WD repeat domain 5 (wdr5-a), WD repeat domain 5 (wdr5-b)

Other aliases include:

SWD3, BIG-3, Big, Big-3, AA408785, AA960360, 2410008O07Rik, MGC114572, zgc:56591, zgc:76895, wu:fk47f04, wdr5-a, MGC80538, wdr5-b, MGC81485, big-3, xwdr5, WDR5, MGC137327

On the protein level the following designations are being used for antigen WD Repeat Domain 5:

WD repeat domain 5 – WD-repeat protein 5 – BMP2-induced 3-kb gene protein – SWD3, Set1c WD40 repeat protein, homolog – WD repeat-containing protein 5 – OTTMUSP00000012976 – OTTMUSP00000012977 – WD repeat-containing protein BIG-3

WD Repeat Domain 5 fulfills a number of functions:

protein binding – histone methyltransferase activity (H3-K4 specific) – methylated histone residue binding

WD Repeat Domain 5 is relevant to the following processes:

nucleus – chromatin modification – regulation of transcription – skeletal system development – transcription – histone H3-K4 methylation – histone lysine methylation

Locations for WD Repeat Domain 5:

histone methyltransferase complex – intracellular – nucleus – MLL1 complex

Source: NCBI Entrez Gene, Gene Ontology