anti-Cow (Bovine) AIFM1 antibody for Western Blotting

Recommended AIFM1 Antibody (supplied by: Log in to see )

Antigen
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
  • aif
  • pdcd8
  • PDCD8
  • AIFM1
  • AIF
  • PCD8
  • CG7263
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • AIFsh2
  • Hq
  • Pdcd8
  • mAIF
  • Aif
  • zgc:91994
  • CMTX4
  • COWCK
  • COXPD6
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • Apoptosis inducing factor
  • apoptosis inducing factor
  • allograft inflammatory factor 1
  • apoptosis-inducing factor, mitochondrion-associated 1
  • aifm1
  • AIFM1
  • AIF
  • aif
  • AIF1
  • Aifm1
Epitope
Middle Region
29
15
14
13
10
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
182
78
75
20
11
11
6
4
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
140
33
8
2
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
160
65
52
36
28
20
13
12
11
6
5
3
3
2
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Catalog No. ABIN2792122
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9059346 ABIN2778665 IHC WB Rabbit C-Term Log in to see Polyclonal
2.9059346 ABIN2792100 IHC WB Rabbit N-Term Log in to see Polyclonal
2.9059346 ABIN4278826 IHC (fro) IHC (p) IP SimWes WB Rabbit AA 151-170 Log in to see Polyclonal
2.9059346 ABIN926855 IHC WB Rabbit N-Term Log in to see Polyclonal
2.9059346 ABIN926871 WB Rabbit Middle Region Log in to see Polyclonal
2.9059346 ABIN2560986 ELISA WB Goat IgG Log in to see Polyclonal
2.9059346 ABIN2560985 ELISA WB Goat IgG Log in to see Polyclonal
1 ABIN2630015 ELISA WB Goat C-Term Log in to see Polyclonal
1 ABIN2613375 ELISA WB Goat AA 183-195, Internal Region Log in to see Polyclonal
1 ABIN2470307 IHC WB Rabbit AA 593-606 Log in to see Polyclonal
1 ABIN4278825 IHC (fro) IHC (p) IP SimWes WB Rabbit AA 151-170 Log in to see Polyclonal

General

Antigen Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
Epitope Middle Region
(29), (15), (14), (13), (10), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(182), (78), (75), (20), (11), (11), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(140), (33), (8), (2)
Clonality
Polyclonal
Conjugate This AIFM1 antibody is un-conjugated
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(160), (65), (52), (36), (28), (20), (13), (12), (11), (6), (5), (3), (3), (2)
Pubmed 1 reference available
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Product Details anti-AIFM1 Antibody

Target Details AIFM1 Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN2792122) Images
Sequence VIFYLRDKVV VGIVLWNIFN RMPIARKIIK DGEQHEDLNE VAKLFNIHED
Predicted Reactivity Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against AIFM1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human AIFM1

Target Details AIFM1

Product Details anti-AIFM1 Antibody Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN2792122) Images back to top
Antigen
Alternative Name AIFM1 (AIFM1 Antibody Abstract)
Background AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alias Symbols: AIF, MGC111425, PDCD8, COXPD6
Protein Interaction Partner: ISG15, STAU1, BAG6, UBC, NEDD8, MDM2, ASB12, RNF2, BMI1, SUZ12, PARK2, BAG3, ADRB2, HDAC11, OXSR1, ILK, PAN2, NOS2, MLH1, CFTR, ESR1, TST, FSCN1, CPOX, SHC1, FBXO6, TSC22D4, CAND1, COPS5, CUL1, CUL2, CUL3, CUL5, TONSL, BLNK, PIDD1, XIAP, AMFR, Tubb4b, Tub
Protein Size: 613
Molecular Weight 67 kDa
Gene ID 9131
NCBI Accession NM_004208, NP_004199
UniProt O95831
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration

Application Details

Product Details anti-AIFM1 Antibody Target Details AIFM1 Handling ProductDetails: References for anti-AIFM1 antibody (ABIN2792122) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 613 AA

Restrictions For Research Use only

Handling

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details ProductDetails: References for anti-AIFM1 antibody (ABIN2792122) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-AIFM1 antibody (ABIN2792122)

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling Images back to top
Background publications

Desmots, Russell, Michel, McKinnon: "Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3264-71, 2008

Images

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN2792122) back to top
Supplier Images
Western Blotting (WB) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (Middle Region) antibody (ABIN2792122) WB Suggested Anti-AIFM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (Middle Region) antibody (ABIN2792122) WB Suggested Anti-AIFM1 Antibody
Titration: 1 ug/ml
Positive ...
Western Blotting (WB) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (Middle Region) antibody (ABIN2792122) WB Suggested Anti-AIFM1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500...