anti-Human AIFM1 antibody for Enzyme Immunoassay

Recommended AIFM1 Antibody (supplied by: Log in to see )

Antigen
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
  • aif
  • pdcd8
  • PDCD8
  • AIFM1
  • AIF
  • PCD8
  • CG7263
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • AIFsh2
  • Hq
  • Pdcd8
  • mAIF
  • Aif
  • zgc:91994
  • CMTX4
  • COWCK
  • COXPD6
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • Apoptosis inducing factor
  • apoptosis inducing factor
  • allograft inflammatory factor 1
  • apoptosis-inducing factor, mitochondrion-associated 1
  • aifm1
  • AIFM1
  • AIF
  • aif
  • AIF1
  • Aifm1
Epitope
AA 593-606, C-Term
29
15
13
12
10
5
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
182
78
75
21
12
12
6
4
3
3
2
1
1
1
1
1
1
1
Host
Rabbit
140
33
8
2
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
160
65
52
36
27
20
13
12
11
5
5
3
3
2
Supplier
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Catalog No. ABIN5554519
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1105269 EIA IF IHC (p) WB Mouse IgG2b Log in to see 4-00E-007 1
1 ABIN5554517 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN5554518 EIA IHC (p) WB Rabbit IgG Intermediate Domain Log in to see Polyclonal
1 ABIN615300 EIA IF IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN615316 EIA IF IHC (p) WB Rabbit AA 593-606 Log in to see Polyclonal

General

Antigen Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
Epitope AA 593-606, C-Term
(29), (15), (13), (12), (10), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(182), (78), (75), (21), (12), (12), (6), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(140), (33), (8), (2)
Clonality
Polyclonal
Conjugate This AIFM1 antibody is un-conjugated
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(160), (65), (52), (36), (27), (20), (13), (12), (11), (5), (5), (3), (3), (2)
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Product Details anti-AIFM1 Antibody

Target Details AIFM1 Application Details Handling Images
Specificity This antibody detects AIF at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat
Purification Affinity chromatography purified via peptide column
Immunogen Peptide corresponding to amino acids 593 to 606 of Human AIF .Remarks: This sequence is identical to those of Mouse and Rat AIF.
Isotype IgG

Target Details AIFM1

Product Details anti-AIFM1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name AIFM1 / AIF (AIFM1 Antibody Abstract)
Background Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins (1). A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF) (2). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection. AIF is highly conserved between human and mouse and widely expressed (2).Synonyms: Apoptosis-inducing factor 1 mitochondrial, PDCD8, Programmed cell death protein 8
Gene ID 9131
NCBI Accession NP_004199
UniProt O95831
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration

Application Details

Product Details anti-AIFM1 Antibody Target Details AIFM1 Handling Images back to top
Application Notes ELISA. Western blot: 0.25 to 1 μg/mL. A 67 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Images back to top
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.