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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Simple Western (SimWes)||2 Antibodies||2 Antibodies||2 Antibodies|
|Western Blotting (WB)||174 Antibodies||67 Antibodies||64 Antibodies|
|Immunoprecipitation (IP)||14 Antibodies||7 Antibodies||7 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||45 Antibodies||18 Antibodies||18 Antibodies|
|Immunohistochemistry (IHC)||56 Antibodies||25 Antibodies||27 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||5 Antibodies||3 Antibodies||3 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Antigen||Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This AIFM1 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-AIFM1 AntibodyTarget Details AIFM1 Application Details Handling References for anti-AIFM1 Antibody (ABIN222988) Images
|Blocking Peptide||Blocking peptide for this product available: ABIN412589|
|Specificity||A ~67 kDa band should be detected.|
|Immunogen||Synthetic peptide surrounding amino acid 520 of human AIF|
Target Details AIFM1Product Details anti-AIFM1 Antibody Application Details Handling References for anti-AIFM1 Antibody (ABIN222988) Images back to top
|Alternative Name||AIF (AIFM1 Antibody Abstract)|
AIF (apoptosis inducing factor) was recently identified that causes chromatin condensation and DNA fragmentation. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and DNA fragmentation, which are the hallmarks of apoptosis. AIF is highly conserved between human and mouse and widely expressed.
Synonyms: AIFM1, PDCD8, MGC111425
|Research Area||Cancer, Apoptosis/Necrosis, Cell Cycle|
Application DetailsProduct Details anti-AIFM1 Antibody Target Details AIFM1 Handling References for anti-AIFM1 Antibody (ABIN222988) Images back to top
Western blotting (0.5-4 μg/mL).
Jurkat cell lysate can be used as a positive control.
However, the optimal conditions for your testing samples should be determined individually.
Country of Animal Origin: China
|Restrictions||For Research Use only|
HandlingProduct Details anti-AIFM1 Antibody Target Details AIFM1 Application Details References for anti-AIFM1 Antibody (ABIN222988) Images back to top
|Buffer||100 μg (0.5 mg/mL) affinity purified rabbit anti-AIF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.|
|Precaution of Use||This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
|Storage Comment||For long-term storage, aliquot and freeze at -70 °C.|
|Expiry Date||12 months|
References for anti-AIFM1 Antibody (ABIN222988)Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling Images back to top
|Product cited in:||
Chang, Lin, Wu, Kuo, Wu, Shieh, Gean, Chen, Chen, Wu, Tai, Tseng: "Mechanisms underlying benzyl alcohol cytotoxicity (triamcinolone acetonide preservative) in human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 7, pp. 4214-22, 2011
Jayanthi, Deng, Noailles, Ladenheim, Cadet: "Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 18, Issue 2, pp. 238-51, 2004
ImagesProduct Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling References for anti-AIFM1 Antibody (ABIN222988) back to top