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Browse our anti-BCL2L1 (BCL2L1) Antibodies

Full name:
anti-BCL2-Like 1 Antibodies (BCL2L1)
On www.antibodies-online.com are 504 BCL2-Like 1 (BCL2L1) Antibodies from 36 different suppliers available. Additionally we are shipping BCL2L1 Kits (22) and BCL2L1 Proteins (17) and many more products for this protein. A total of 566 BCL2L1 products are currently listed.
Synonyms:
Bcl(X)L, bcl-X, bcl-x(l), bcl-xl, BCL-XL/S, Bcl-Xs, Bcl2l, BCL2L1, Bclx, BCLXL, BCLXS, PPP1R52, xR11
list all antibodies Gene Name GeneID UniProt
BCL2L1 60480  
BCL2L1 598 Q07817
BCL2L1 24888 P53563

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Most Popular Reactivities for anti-BCL2L1 (BCL2L1) Antibodies

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anti-Mouse (Murine) BCL2L1 Antibodies:

anti-Human BCL2L1 Antibodies:

anti-Rat (Rattus) BCL2L1 Antibodies:

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Top referenced anti-BCL2L1 Antibodies

  1. Human Monoclonal BCL2L1 Primary Antibody for WB - ABIN967300 : Hsu, Wolter, Youle: Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 4 references for ABIN967300

  2. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1531788 : Cheng, Levine, Boise, Thompson, Hardwick: Bax-independent inhibition of apoptosis by Bcl-XL. in Nature 1996 (PubMed)
    Show all 3 references for ABIN1531788

  3. Human Monoclonal BCL2L1 Primary Antibody for FACS, IF - ABIN180627 : Hsu, Youle: Nonionic detergents induce dimerization among members of the Bcl-2 family. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 references for ABIN180627

  4. Human Polyclonal BCL2L1 Primary Antibody for IP, WB - ABIN223050 : Cordiali-Fei, Ardigo, Mastroianni, Giuliani, D Agosto, Bordignon, Trento, Vento, Berardesca: Serum cytokines and biohumoral immunological characterization of psoriatic patients in long term etanercept treatment. in International journal of immunopathology and pharmacology 2008 (PubMed)
    Show all 3 references for ABIN223050

  5. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1532818 : Sattler, Liang, Nettesheim, Meadows, Harlan, Eberstadt, Yoon, Shuker, Chang, Minn, Thompson, Fesik: Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 3 references for ABIN1532818

  6. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1533140 : Boise, González-García, Postema, Ding, Lindsten, Turka, Mao, Nuñez, Thompson: bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. in Cell 1993 (PubMed)
    Show all 2 references for ABIN1533140

  7. Human Polyclonal BCL2L1 Primary Antibody for IHC, ELISA - ABIN1532107 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Show all 2 references for ABIN1532107

  8. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2779336 : ONeill, Manion, Maguire, Hockenbery: BCL-XL dimerization by three-dimensional domain swapping. in Journal of molecular biology 2006 (PubMed)

  9. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2792119 : Xu, Xu, Palmer, Reed: BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins. in The Journal of biological chemistry 2008 (PubMed)

  10. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody for WB - ABIN2774598 : Bachelor, Bowden: Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against BCL2L1 Interaction Partners

Mouse (Murine) BCL2-Like 1 (BCL2L1) interaction partners

  1. Bcl-xL deficiency induced apoptosis in a select population of differentiated neurons and led to severe neurobehavioral abnormalities.

  2. loss of PUMA (show BBC3 Antibodies) had no impact on the loss of platelets caused by loss of BCL-XL. It therefore remains to be established whether other BH3-only (show BBC3 Antibodies) proteins play a critical role in induction of apoptosis in platelets or whether their death is controlled solely by the interactions between BCL-XL with BAK (show BAK1 Antibodies) and BAX (show BAX Antibodies).

  3. MLF1 (show MLF1 Antibodies) is negatively regulated by 14-3-3 (show YWHAQ Antibodies) via binding to, and blocking, MLF1 (show MLF1 Antibodies)'s Bcl-2 (show BCL2 Antibodies) homology domain 3 and thereby preventing Bcl-XL from associating with MLF1 (show MLF1 Antibodies).

  4. Genetic and pharmacological inhibition of BCL-W (show BCL2L2 Antibodies) and BCL-XL causes directed elimination of senescent cells.

  5. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (show NFE2L2 Antibodies) and Bcl-xL.

  6. The influence of chronic ethanol consumption on the expression of the Bdnf (show BDNF Antibodies), Bax (show BAX Antibodies), Bcl-xL, and CASP3 (show CASP3 Antibodies) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  7. despite its role in Bax (show BAX Antibodies) inhibition, Bcl-xL also primes mitochondria to permeabilization and cytochrome c (show CYCS Antibodies) release.

  8. These findings indicate that eosinophil survival is largely regulated by betac chain-induced NF-kappaB (show NFKB1 Antibodies) activation and subsequent induction of Bcl-x

  9. these data indicate that beta-cell apoptosis is, in part, attributable to the modulation of 5'SS selection in the Bcl-x pre-mRNA by bioactive lipids modulated by iPLA2beta (show PLA2G6 Antibodies).

  10. only loss of both Bclx alleles markedly forestalled tumorigenesis, loss of a single Bim (show BCL2L11 Antibodies) allele overcame this blockade.

Human BCL2-Like 1 (BCL2L1) interaction partners

  1. in addition to MCL-1 (show MCL1 Antibodies), BCL-XL is heterogeneously expressed in HMCLs and patient samples. The expression profile of BCL-XL relative to BCL-2 (show BCL2 Antibodies) and MCL-1 (show MCL1 Antibodies) may be an important predictor of response to venetoclax sensitivity as a monotherapy and in combination with bortezomib.

  2. Mono treatment with lexatumumab was not sufficient to induce apoptosis in pancreatic cancer cells, whereas focal adhesion kinase inhibitor PF573228 significantly sensitized lexatumumab-induced apoptosis. Western blotting analysis revealed that lexatumumab and PF573228 combination treatment increased death receptor 5 (show TNFRSF10B Antibodies) but decreased Bcl-xL expression.

  3. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (show HIF1A Antibodies) or Bcl-xL, binding proteins of IPAS (show HIF3A Antibodies) in the nucleus and mitochondria, respectively.

  4. mechanistic studies, inhibition of SRC (show SRC Antibodies) and PKCdelta (show PKCd Antibodies) completely ablated the ability of MDA-7/IL-24 (show IL24 Antibodies) to reduce the Bcl-x(L)/(s) mRNA ratio and cell viability. These findings show that Bcl-x(s) expression is an important mediator of MDA-7/IL-24 (show IL24 Antibodies)-induced cytotoxicity requiring the SRC (show SRC Antibodies)/PKCdelta (show PKCd Antibodies) signaling axis in NSCLC cells.

  5. Resistance induced in newly formed cancer stem cells is mediated by the anti-apoptotic molecule BCL-XL and inhibition of BCL-XL with the BH3 mimetic ABT-737 sensitizes these cancer cells toward chemotherapy.

  6. we discovered that deletions involving the PARK2 (show PARK2 Antibodies) gene are significantly anti-correlated with focal amplifications of the gene encoding BCL-XL.

  7. The C-terminal tail of BCL-XL forms a membrane-embedded alpha-helix that anchors the protein's globular head to the lipid bilayer membrane, yet retains a significant degree of conformational dynamics.

  8. Bcl-xL overexpression may be closely related to the dynamic of the pathogenesis and development of tongue carcinoma.

  9. Results provide evidence that microRNA 421 induces apoptosis of cervical cancer cells via down-regulation of Bcl-xL.

  10. We conclude that Bcl-x plays a role in regulation of HSC (show FUT1 Antibodies) apoptosis and modulation of Bcl-x alternative splicing may become a novel molecular therapy for liver fibrosis.

Pig (Porcine) BCL2-Like 1 (BCL2L1) interaction partners

  1. interleukin-6 (show IL6 Antibodies), endothelin ET-1 (show EDN1 Antibodies), and apoptotic Bak (show BAK1 Antibodies) and Bcl-XL genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bcl-xL was significantly decreased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

  3. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (show BCL2 Antibodies) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  4. Bcl-Xl deamidation and methylation has a role in protein isoaspartate methyltransferase prevention of apoptosis induced by oxidative stress in endothelial cells

  5. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (show TNF Antibodies), IL-6 (show IL6 Antibodies), IL-12p40, IL-1beta (show IL1B Antibodies), and resulted in increased expression of the apoptosis initiator caspase-8 (show CASP8 Antibodies) and bcl2L1.

Cow (Bovine) BCL2-Like 1 (BCL2L1) interaction partners

  1. amplification and characterization of partial regions of exons 2 and 3 of the bovine BCL2L1 gene

  2. Data show that Bcl-x(L) expression is increased in the pulmonary artery undergoing chronic pulmonary vascular remodeling.

Rabbit BCL2-Like 1 (BCL2L1) interaction partners

  1. This study leads to conclude that BCLXL peak expression at the zygotic genome activation phase may be a requirement for embryo development

  2. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2L1 transcripts and protein depending on luteal stage.

Xenopus laevis BCL2-Like 1 (BCL2L1) interaction partners

  1. repression of radiation-induced apoptosis by overexpression of Bcl-xL during embryonic development depends upon the timing of its expression and post-translational events that enable the protein to become effective

BCL2L1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

Alternative names and synonyms associated with BCL2L1

  • BCL2-like 1 (bcl2l1) antibody
  • BCL2-like 1 (BCL2L1) antibody
  • BCL2-like 1 (LOC100224900) antibody
  • transgene insertion 2, Craig B Thompson (Tg(BCL2L1)2Cbt) antibody
  • BCL2-like 1 (Bcl2l1) antibody
  • Bcl2-like 1 (Bcl2l1) antibody
  • Bcl(X)L antibody
  • bcl-X antibody
  • bcl-x(l) antibody
  • bcl-xl antibody
  • BCL-XL/S antibody
  • Bcl-Xs antibody
  • Bcl2l antibody
  • BCL2L1 antibody
  • Bclx antibody
  • BCLXL antibody
  • BCLXS antibody
  • PPP1R52 antibody
  • xR11 antibody

Protein level used designations for anti-BCL2-Like 1 (BCL2L1) Antibodies

BCL2-like 1 , apoptosis regulator Bcl-X , bcl-2-like protein 1 , protein phosphatase 1, regulatory subunit 52 , B-cell leukemia/lymphoma x , anti-apoptosis regulatory protein , bcl2-L-1 , B cell lymphoma 2 like , B cell lymphoma like X , anti-apoptotic Bcl-xL , BCL2-like protein 1 , Bcl-X , BCLX protein , apoptosis regulator R11

GENE ID SPECIES
447991 Xenopus (Silurana) tropicalis
458156 Pan troglodytes
100224900 Taeniopygia guttata
60480 Mus musculus
598 Homo sapiens
12048 Mus musculus
24888 Rattus norvegicus
397536 Sus scrofa
403618 Canis lupus familiaris
282152 Bos taurus
100008875 Oryctolagus cuniculus
493701 Felis catus
443061 Ovis aries
373954 Gallus gallus
398251 Xenopus laevis
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