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|Application / Reactivity||Rat (Rattus)||Mouse (Murine)|
|ELISA||36 Antibodies||38 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies||3 Antibodies|
|Flow Cytometry (FACS)||15 Antibodies||21 Antibodies|
|Immunochromatography (IC)||3 Antibodies||2 Antibodies|
|Immunocytochemistry (ICC)||9 Antibodies|
|Immunofluorescence (IF)||42 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||25 Antibodies|
|Immunohistochemistry (IHC)||75 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||5 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||21 Antibodies|
|Immunoprecipitation (IP)||12 Antibodies|
|Western Blotting (WB)||104 Antibodies|
|Antigen||BCL2-Like 1 (BCL2L1) Antibodies|
|Epitope||AA 18-233 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This BCL2L1 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-BCL2L1 AntibodyTarget Details BCL2L1 Application Details Handling References for anti-BCL2L1 Antibody (ABIN968153) Images
|Cross-Reactivity||Mouse (Murine), Rat (Rattus)|
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
|Purification||The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|Immunogen||Human Bcl-xl aa. 18-233|
Target Details BCL2L1Product Details anti-BCL2L1 Antibody Application Details Handling References for anti-BCL2L1 Antibody (ABIN968153) Images back to top
|Alternative Name||Bcl-x (BCL2L1 Antibody Abstract)|
|Background||Bcl-x is related to the Bcl-2 protein and can function independently of Bcl-2 in regulating apoptosis (programmed cell death). The bcl-x transcript is expressed in a number of tissues, with the highest levels in the lymphoid and central nervous systems. Two distinct cDNA species, bcl-xL and bcl-xS, have been observed and appear to arise from alternate 5' splice sites located within the first coding exon of the bcl-x gene. Bcl-xL is composed of 233 amino acids and is similar in size and structure to Bcl-2. The Bcl-xS polypeptide shows a deletion of 63 amino acids which consist of the region of Bcl-xL with the highest degree of amino acid identity to Bcl-2. Like Bcl-2, Bcl-xL inhibits cell death upon growth factor withdrawal when transfected into an IL-3-dependent cell line. However, Bcl-xS inhibits Bcl-2 mediated cell survival.|
|Molecular Weight||26 kDa|
Application DetailsProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Handling References for anti-BCL2L1 Antibody (ABIN968153) Images back to top
Related Products: ABIN968536, ABIN967389
|Restrictions||For Research Use only|
HandlingProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details References for anti-BCL2L1 Antibody (ABIN968153) Images back to top
|Buffer||Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store undiluted at -20° C.|
References for anti-BCL2L1 Antibody (ABIN968153)Product Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Handling Images back to top
|Product cited in:||
Devarajan, De Leon, Talasazan et al.: "The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40599-605, 2001 (PubMed).
Oetzel, Jonuleit, Götz et al.: "The tyrosine kinase inhibitor CGP 57148 (ST1 571) induces apoptosis in BCR-ABL-positive cells by down-regulating BCL-X." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 6, Issue 5, pp. 1958-68, 2000 (PubMed).
Soini, Kinnula, Kaarteenaho-Wiik et al.: "Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 11, pp. 3508-15, 2000 (PubMed).
Kishimoto, Sprent: "Strong TCR ligation without costimulation causes rapid onset of Fas-dependent apoptosis of naive murine CD4+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 4, pp. 1817-26, 1999 (PubMed).
Anderson, Teutsch, Dong et al.: "An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 20, pp. 10966-71, 1996 (PubMed).
ImagesProduct Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Handling References for anti-BCL2L1 Antibody (ABIN968153) back to top