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anti-Mouse (Murine) BCL2L1 antibody for Immunohistochemistry (Frozen Sections)

Recommended BCL2L1 Antibody (supplied by: Log in to see )

Antigen
BCL2-Like 1 (BCL2L1) Antibodies
  • Bcl(X)L
  • Bcl-X
  • bcl-x
  • bcl-X
  • bcl-x(l)
  • Bcl-xl
  • bcl-xl
  • bcl-XL
  • bcl-xL
  • Bcl-XL
  • BCL-XL
  • Bcl-xL
  • BCL-XL/S
  • bcl-xl/s
  • bcl-xs
  • Bcl-Xs
  • Bcl-xS
  • bcl-xS
  • Bcl2l
  • bcl2l
  • BCL2L
  • BCL2L1
  • BclX
  • Bclx
  • BCLX
  • bclx
  • bclxl
  • BCLXL
  • BCLXS
  • PPP1R52
  • xR11
Reactivity
Human, Mouse (Murine), Rat (Rattus)
478
303
276
137
16
8
6
5
4
3
2
2
2
1
Host
Mouse
281
231
3
3
Clonality
Monoclonal
Conjugate
This BCL2L1 antibody is un-conjugated
23
15
10
9
7
7
6
5
5
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
401
190
165
156
144
125
124
95
90
23
7
4
3
3
2
1
1
Supplier
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Catalog No. ABIN371611
$ 467.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088254584 ABIN1077850 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 2-212 Log in to see Polyclonal
0.00088254584 ABIN184367 IHC (fro) IP WB Rabbit Log in to see Polyclonal
0.00088254584 ABIN4283650 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283651 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283652 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283653 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see SPM165
0.00088254584 ABIN4283654 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see SPM165
0.00088254584 ABIN4283655 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see SPM165
0.00088254584 ABIN4283656 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see 2H12
0.00088254584 ABIN4283657 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see 2H12
0.00088254584 ABIN4283658 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 3-14 Log in to see 2H12
0.00088254584 ABIN4283661 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 405 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283662 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283663 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 647 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283664 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Alexa Fluor 700 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283665 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Allophycocyanin Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283666 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Biotin Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283667 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 650 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283668 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 680 Mouse IgG2a AA 3-14 Log in to see BX006
0.00088254584 ABIN4283669 ELISA FACS ICC IF IHC (fro) IHC (p) IP WB DyLight 488 Mouse IgG2a AA 3-14 Log in to see BX006

Top referenced anti-BCL2L1 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-BCL2L1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 68 Antibodies 70 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 3 Antibodies
Flow Cytometry (FACS) 109 Antibodies 115 Antibodies
Immunochromatography (IC) 3 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 81 Antibodies
Immunofluorescence (IF) 119 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 90 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 82 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 134 Antibodies
Immunoprecipitation (IP) 89 Antibodies
Western Blotting (WB) 228 Antibodies

General

Antigen BCL2-Like 1 (BCL2L1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(478), (303), (276), (137), (16), (8), (6), (5), (4), (3), (2), (2), (2), (1)
Host Mouse
(281), (231), (3), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL2L1 antibody is un-conjugated
(23), (15), (10), (9), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(401), (190), (165), (156), (144), (125), (124), (95), (90), (23), (7), (4), (3), (3), (2), (1), (1)
Pubmed 15 references available
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Product Details anti-BCL2L1 Antibody

Target Details BCL2L1 Application Details Handling References for anti-BCL2L1 Antibody (ABIN371611) Images
Specificity This antibody recognizes Bcl-xL.
Characteristics Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
Purification Purified
Immunogen Recombinant Bcl-xS.
Clone 7B2-5
Isotype IgG3

Target Details BCL2L1

Product Details anti-BCL2L1 Antibody Application Details Handling References for anti-BCL2L1 Antibody (ABIN371611) Images back to top
Antigen
Alternative Name Bcl-2-Like 1 (BCL2L1 Antibody Abstract)
Background Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. (Ref.1) It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. (Ref.2) Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis (Ref.3,4) while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. (Ref.5-8) Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. (Ref.9-13) In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2. (Ref.5,14) Other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity. (Ref.15,16)Synonyms: BCL2L, BCL2L1, BCLX, Bcl-2-like protein 1, Bcl-x, Bcl2-L-1, bcl-xL, bcl-xS
UniProt Q07817
Research Area Cancer
Pathways Apoptosis

Application Details

Product Details anti-BCL2L1 Antibody Target Details BCL2L1 Handling References for anti-BCL2L1 Antibody (ABIN371611) Images back to top
Application Notes Flow Cytometry: < / = 3 μg/10^6 cells. Western Blot: < / = 0.5 μg/mL. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details References for anti-BCL2L1 Antibody (ABIN371611) Images back to top
Concentration 0.1 mg/mL
Buffer 100 mM Borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-BCL2L1 Antibody (ABIN371611)

Product Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Handling Images back to top
Background publications

Gottschalk, Boise, Oltvai, Accavitti, Korsmeyer, Quintáns, Thompson: "The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." in: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, 2006

Nuñez, Clarke: "The Bcl-2 family of proteins: regulators of cell death and survival." in: Trends in cell biology, Vol. 4, Issue 11, pp. 399-403, 2004

Cheng, Levine, Boise, Thompson, Hardwick: "Bax-independent inhibition of apoptosis by Bcl-XL." in: Nature, Vol. 379, Issue 6565, pp. 554-6, 1996

Cory: "Regulation of lymphocyte survival by the bcl-2 gene family." in: Annual review of immunology, Vol. 13, pp. 513-43, 1995

Farrow, White, Martinou, Raven, Pun, Grinham, Martinou, Brown: "Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K." in: Nature, Vol. 374, Issue 6524, pp. 731-3, 1995

Chittenden, Harrington, OConnor, Flemington, Lutz, Evan, Guild: "Induction of apoptosis by the Bcl-2 homologue Bak." in: Nature, Vol. 374, Issue 6524, pp. 733-6, 1995

Kiefer, Brauer, Powers, Wu, Umansky, Tomei, Barr: "Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak." in: Nature, Vol. 374, Issue 6524, pp. 736-9, 1995

Dole, Jasty, Cooper, Thompson, Nuñez, Castle: "Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis." in: Cancer research, Vol. 55, Issue 12, pp. 2576-82, 1995

Shimizu, Eguchi, Kosaka, Kamiike, Matsuda, Tsujimoto: "Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL." in: Nature, Vol. 374, Issue 6525, pp. 811-3, 1995

González-García, García, Ding, OShea, Boise, Thompson, Núñez: "bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 10, pp. 4304-8, 1995

Yin, Oltvai, Korsmeyer: "BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax." in: Nature, Vol. 369, Issue 6478, pp. 321-3, 1994

Gottschalk, Boise, Thompson, Quintáns: "Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 15, pp. 7350-4, 1994

Oltvai, Milliman, Korsmeyer: "Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death." in: Cell, Vol. 74, Issue 4, pp. 609-19, 1993

Boise, González-García, Postema, Ding, Lindsten, Turka, Mao, Nuñez, Thompson: "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death." in: Cell, Vol. 74, Issue 4, pp. 597-608, 1993

Cohen: "Programmed cell death in the immune system." in: Advances in immunology, Vol. 50, pp. 55-85, 1991

Images

Product Details anti-BCL2L1 Antibody Target Details BCL2L1 Application Details Handling References for anti-BCL2L1 Antibody (ABIN371611) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-BCL2L1 antibody (BCL2-Like 1) (ABIN371611) anti-BCL2-Like 1 (BCL2L1) antibody