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anti-Mouse (Murine) BIRC5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended BIRC5 Antibody (supplied by: Log in to see )

Antigen
Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
  • AAC-11
  • AP14
  • API4
  • Api4
  • EPR-1
  • survivin40
  • TIAP
Epitope
C-Term
20
5
4
4
3
3
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
66
34
10
1
1
1
Host
Rabbit
57
22
3
Clonality
Polyclonal
Conjugate
This BIRC5 antibody is un-conjugated
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
59
25
20
13
13
7
5
3
2
2
1
1
1
Supplier
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Catalog No. ABIN500292
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34274516 ABIN1449649 EIA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089834916 ABIN181412 IHC (p) Rabbit C-Term Log in to see Polyclonal 3
0.00089834916 ABIN181413 IHC (p) Rabbit C-Term Log in to see Polyclonal 2
0.00089834916 ABIN115386 IHC (p) Rabbit C-Term Log in to see Polyclonal 4
0.00089834916 ABIN115387 IHC (p) Rabbit C-Term Log in to see Polyclonal 3
0.00089834916 ABIN272115 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089834916 ABIN372971 IHC (p) Rabbit C-Term Log in to see Polyclonal
0.00089834916 ABIN373937 IHC (p) Rabbit C-Term Log in to see Polyclonal

Top referenced anti-BIRC5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-BIRC5 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 8 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunohistochemistry (IHC) 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Western Blotting (WB) 21 Antibodies

General

Antigen Baculoviral IAP Repeat-Containing 5 (BIRC5) Antibodies
Epitope C-Term
(20), (5), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(66), (34), (10), (1), (1), (1)
Host Rabbit
(57), (22), (3)
Clonality
Polyclonal
Conjugate This BIRC5 antibody is un-conjugated
(2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(59), (25), (20), (13), (13), (7), (5), (3), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-BIRC5 Antibody

Target Details BIRC5 Application Details Handling References for anti-BIRC5 Antibody (ABIN500292) Images
Specificity This antibody detects IAP4 / BIRC5 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Mouse
Purification Peptide affinity chromatography
Immunogen Survivin antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of mouse Survivin.
Isotype IgG

Target Details BIRC5

Product Details anti-BIRC5 Antibody Application Details Handling References for anti-BIRC5 Antibody (ABIN500292) Images back to top
Antigen
Alternative Name IAP4 / BIRC5 (BIRC5 Antibody Abstract)
Background Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP (1-3). Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas (1,3).Synonyms: API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, Survivin
Gene ID 11799
UniProt O70201
Research Area Cancer, Apoptosis/Necrosis, Neurology
Pathways Apoptosis, Cell Division Cycle

Application Details

Product Details anti-BIRC5 Antibody Target Details BIRC5 Handling References for anti-BIRC5 Antibody (ABIN500292) Images back to top
Application Notes ELISA. Western blot: 1 to 2 μg/mL, an approximate 17 kDa band can be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details References for anti-BIRC5 Antibody (ABIN500292) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-BIRC5 Antibody (ABIN500292)

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details Handling Images back to top
Background publications

Ambrosini, Adida, Altieri: "A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma." in: Nature medicine, Vol. 3, Issue 8, pp. 917-21, 1997

Images

Product Details anti-BIRC5 Antibody Target Details BIRC5 Application Details Handling References for anti-BIRC5 Antibody (ABIN500292) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BIRC5 antibody (Baculoviral IAP Repeat-Containing 5) (C-Term) (ABIN500292) Immunohistochemistry of Survivin in mouse spleen cells with AP30567PU-Nat 10 µg/ml.
Western Blotting (WB) image for anti-BIRC5 antibody (Baculoviral IAP Repeat-Containing 5) (C-Term) (ABIN500292) Western blot analysis of survivin in mouse spleen tissue lysate with this product at ...