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Browse our anti-CAPN2 (CAPN2) Antibodies

Full name:
anti-Calpain 2, (M/II) Large Subunit Antibodies (CAPN2)
On are 30 Calpain 2, (M/II) Large Subunit (CAPN2) Antibodies from 12 different suppliers available. Additionally we are shipping CAPN2 Kits (14) and CAPN2 Proteins (7) and many more products for this protein. A total of 52 CAPN2 products are currently listed.
AI326419, CANP2, CANP 2, CANPL2, CANPml, Capa-2, Capa2, m-calpain, m-calpin, mCANP
list all antibodies Gene Name GeneID UniProt
CAPN2 12334 O08529
CAPN2 824 P17655
CAPN2 29154 Q07009

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Most Popular Reactivities for anti-CAPN2 (CAPN2) Antibodies

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anti-Mouse (Murine) CAPN2 Antibodies:

anti-Human CAPN2 Antibodies:

anti-Rat (Rattus) CAPN2 Antibodies:

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More Antibodies against CAPN2 Interaction Partners

Mouse (Murine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.

  2. LOX-1 (show OLR1 Antibodies) is, at least in part, responsible for the inhibitory effect of ox-LDL on macrophage migration and this process involves calpain-1 (show CAPN1 Antibodies) and -2.

  3. Dicer is predominantly (show CA2 Antibodies) a Capn2 substrate. Dicer levels were altered in platelets from diabetic mice due to the cleavage (show DICER1 Antibodies) of the enzyme by calpain, resulting in loss of function.

  4. Data suggest that vitamin D3 up-regulates skeletal muscle fat deposition, up-regulates muscle m-calpain/Capn2 and u-calpain/Capn1 expression, and down-regulates muscle calpastatin expression.

  5. Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 (show CAPN1 Antibodies) deficient mice.

  6. Calpain-mediated proteolysis of tropomodulin isoforms TMOD1 (show TMOD1 Antibodies) and TMOD4 (show TMOD4 Antibodies) leads to thin filament elongation in dystrophic skeletal muscle.

  7. extrasynaptic NMDAR (show GRIN1 Antibodies)-coupled m-calpain activation is neurodegenerative

  8. Down-regulated expression of calpain-2 or talin-1, or pharmacological interference with calpain action, did not affect toxin binding but reduced endocytosis and increased the survival of cells exposed to anthrax lethal toxin.

  9. The carboxyl tail of alpha-actinin-4 (show ACTN4 Antibodies) regulates its susceptibility to m-calpain and thus functions in cell migration and spreading.

  10. Calpain-2 was required for FFA-induced expression of CHOP (show DDIT3 Antibodies) and activation of caspase-12 (show CASP12 Antibodies) and caspase-3 (show CASP3 Antibodies), thus promoting cell apoptosis in beta-TC3 cells.

Human Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. the expression of CAPN2 was elevated in prostate cancer tissues than that in normal control tissues.

  2. our findings suggest that the gene/protein expression of both CAPN1 (show CAPNL1 Antibodies) and CAPN2, as well as the ERK1 (show MAPK3 Antibodies) and ERK2 (show MAPK1 Antibodies) genes and related proteins, could be molecular factors associated with more invasive tumor behavior in squamous cell laryngeal cancer.

  3. Calpain 2-mediated cleavage of Atg3 (show ATG3 Antibodies) and Atg7 (show ATG7 Antibodies) accounts for the impaired autophagy.

  4. Calcineurin (show PPP3CA Antibodies) together with its upstream molecule, calpain 2, and its downstream effector, NFAT (show NFATC1 Antibodies)-c3, might contribute to the development of atrial fibrillation in patients with heart valve disease and diabetes.

  5. Calpain-2 modulates pulmonary vascular remodeling in pulmonary arterial hypertension.

  6. Taken together, our results demonstrated the deregulation of GAS2 (show GAS2 Antibodies) in both AML (show RUNX1 Antibodies) and ALL and the requirement of GAS2 (show GAS2 Antibodies)-Calpain2 axis for the growth of leukemic cells.

  7. The combination of Ca2 (show CA2 Antibodies)+ and ionomycin was required to activate calpain 2, resulting in the further degradation of Dicer (show DICER1 Antibodies) and the appearance of a degradation product similar to that detected in platelets from some diabetic individuals.

  8. In a transgenic mouse model, hypoxia-triggered m-calpain activation is involved in endoplasmic reticulum stress-mediated Alzheimer's disease pathogenesis.

  9. Small interfering RNA (siRNA)-mediated silencing of m-calpain expression significantly suppressed the adhesive, migrative and invasive potentials of human hepatoma cells.

  10. The data reveal that hGAAP is a novel regulator of focal adhesion dynamics, cell adhesion, and migration by controlling localized Ca(2 (show CA2 Antibodies)+)-dependent activation of calpain 2.

Cow (Bovine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. m- and micro-calpain immunosignals in the cytoplasm both along the Z disk/I band regions and in the form of intracellular stores.

  2. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain/HhaI, and UCP-3 (show UCP3 Antibodies)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  3. The cleavage of NCX1 (show SLC8A1 Antibodies) by m-calpain in the caveolae vesicles may be interpreted as an important mechanism of Ca(2 (show CA2 Antibodies)+) overload

  4. characteristic properties of ER membrane m-calpain (MCp (show CD46 Antibodies)), calpastatins and lumen m-calpain (LCp (show KLHDC2 Antibodies)) and a brief comparative study between MCp (show CD46 Antibodies) and LCp (show KLHDC2 Antibodies)

Pig (Porcine) Calpain 2, (M/II) Large Subunit (CAPN2) interaction partners

  1. Calpain-2 plays an important role in lung endothelial cell migration and proliferation.

  2. The Decreased expression of calpain 2 mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

CAPN2 Antigen Profile

Antigen Summary

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CAPN2

  • calpain 2 (Capn2) antibody
  • calpain 2, (m/II) large subunit (CAPN2) antibody
  • calpain 2, (m/II) large subunit (Capn2) antibody
  • AI326419 antibody
  • CANP2 antibody
  • CANP 2 antibody
  • CANPL2 antibody
  • CANPml antibody
  • Capa-2 antibody
  • Capa2 antibody
  • m-calpain antibody
  • m-calpin antibody
  • mCANP antibody

Protein level used designations for CAPN2

80 kDa M-calpain subunit , CALP80 , CANP 2 , calcium-activated neutral proteinase 2 , calpain M-type , calpain-2 catalytic subunit , calpain-2 large subunit , cysteine proteinase , m-calpain 80 kDa large subunit , m-calpain large subunit , millimolar-calpain , M-calpain , calpain 2, large [catalytic] subunit , calpain 2, large subunit , calpain large polypeptide L2 , calpain, large polypeptide L2 , mCL , calpain II

12334 Mus musculus
824 Homo sapiens
29154 Rattus norvegicus
281662 Bos taurus
395963 Gallus gallus
397393 Sus scrofa
100009092 Oryctolagus cuniculus
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