anti-Gibbon Caspase 1 antibody for Immunohistochemistry

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 1
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1-like
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Ice
  • AaeL_AAEL014348
  • LOC100725217
  • LOC100101588
Epitope
AA 371 - 390
38
15
13
12
10
10
7
6
6
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Gibbon, Gorilla, Human
252
94
73
8
3
2
2
1
1
1
1
1
Host
Mouse
236
39
8
2
Clonality
Monoclonal
Conjugate
This Caspase 1 antibody is un-conjugated
18
14
7
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
252
137
116
84
32
26
16
6
6
5
3
3
1
Supplier
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Catalog No. ABIN2469580
$ 515.63
Plus shipping costs $45.00

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope AA 371 - 390
(38), (15), (13), (12), (10), (10), (7), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Gibbon, Gorilla, Human
(252), (94), (73), (8), (3), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(236), (39), (8), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 1 antibody is un-conjugated
(18), (14), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(252), (137), (116), (84), (32), (26), (16), (6), (6), (5), (3), (3), (1)
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling Images
Purification Protein G Column
Immunogen Caspase-1 monoclonal antibody was raised against amino acids 371 - 390 of Caspase-1 (Human).
Clone 14F468
Isotype IgG1

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-1 (CASP1 Antibody Abstract)
Background Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into tetramer to form the active enzyme. Caspase-1/ICE (IL-1b converting enzyme) is similar to the cell death gene CED-3 of Caenorhabditilis elegans and regulates multiple proinflammatory cytokines, including interleukin-1b and interferon-gamma-inducing factor. Caspase 1, also called interleukin-1 beta converting enzyme, is a cysteine C14 endopeptidase able to process pro-interleukin-1 beta into its active form. Caspase 1 is identical to Caenorhabditis elegans cell death gene ced-3 and may be involved in apoptotic signalling. Inhibition of caspase-1 in mice models extended survival and delayed appearance of neuronal inclusions and symptoms of Huntingdon disease.
Gene ID 834
UniProt P29466
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling Images back to top
Application Notes Caspase-1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Images back to top
Format Liquid
Buffer PBS, 0.2 % gelatin, 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store Caspase-1 antibody at 4 °C or -20 °C.