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anti-Human Caspase 1 antibody for Enzyme Immunoassay

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • CASP1
  • ccp1
  • CG5370
  • dcp-1
  • DCP-1
  • dcp1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ICE
  • Ice
  • Il1bc
  • IL1BC
  • l(2)01862
  • l(2)02132
  • P45
Epitope
Intermediate Domain
39
15
14
11
10
10
6
5
5
5
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
246
75
53
8
2
2
1
1
1
1
1
1
Host
Rabbit
231
37
10
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
19
14
8
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
226
129
119
76
23
19
16
6
6
4
3
3
2
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Catalog No. ABIN499543
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008788108 ABIN499541 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 1
0.0008788108 ABIN615246 EIA IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008788108 ABIN615247 EIA IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-Caspase 1 antibody for Enzyme Immunoassay

Similar anti-Caspase 1 Antibodies

Application / Reactivity Human
ELISA 101 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 13 Antibodies
Immunofluorescence (IF) 19 Antibodies
Immunohistochemistry (IHC) 122 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 74 Antibodies
Immunoprecipitation (IP) 21 Antibodies
Western Blotting (WB) 205 Antibodies

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope Intermediate Domain
(39), (15), (14), (11), (10), (10), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(246), (75), (53), (8), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(231), (37), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(19), (14), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(226), (129), (119), (76), (23), (19), (16), (6), (6), (4), (3), (3), (2)
Pubmed 4 references available
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN499543) Images
Specificity Caspase-1 antibody was raised against a 15 amino acid peptide from near the middle of human Caspase-1.
Purification Affinity chromatography purified via peptide column
Immunogen Human Casp-1 / ICE / IL-1b converting enzyme (Intermediate Domain) Peptide
Isotype IgG

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 Antibody (ABIN499543) Images back to top
Antigen
Alternative Name Caspase-1 (CASP1 Antibody Abstract)
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1beta and IL-18 (3,4). Caspase-1 was initially identified as an IL-1beta-converting enzyme (5), later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 (6) whose overexpression can induce apoptosis in fibroblasts (7).Synonyms: CASP-1, CASP1, ICE, IL1BC, IL1BCE, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Gene ID 834
NCBI Accession NP_150634
UniProt P29466
Research Area Apoptosis/Necrosis
Pathways Apoptosis

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 Antibody (ABIN499543) Images back to top
Application Notes ELISA. Western Blot: Casp-1 antibody can be used for the detection of Caspase-1 at 0.5 μg/mL. Depending on cell lines or tissues used, other cleavage products may be observed. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 Antibody (ABIN499543) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-Caspase 1 Antibody (ABIN499543)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Background publications

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003

Kuida, Lippke, Ku, Harding, Livingston, Su, Flavell: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN499543) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 antibody (CASP1) (Intermediate Domain) (ABIN499543) Immunohistochemistry of caspase-1 in human spleen tissue with caspase-1 antibody at 1...
Western Blotting (WB) image for anti-Caspase 1 antibody (CASP1) (Intermediate Domain) (ABIN499543) Western blot analysis of Caspase-1 in HeLa cell lysate with AP30188PU-N Caspase-1 ant...