anti-Human Caspase 1 antibody for Western Blotting

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 1
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1-like
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Ice
  • AaeL_AAEL014348
  • LOC100725217
  • LOC100101588
Epitope
Middle Region
38
15
13
12
10
9
7
6
6
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Horse (Equine), Human, Rabbit, Yeast
252
94
73
8
2
2
2
1
1
1
1
1
Host
Rabbit
235
40
8
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
18
14
7
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
252
138
116
84
32
26
16
6
6
5
3
3
1
Options
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Catalog No. ABIN2787901
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9058776 ABIN3043221 IHC (p) WB Rabbit IgG AA 135-152, N-Term Log in to see Polyclonal 21
2.9058776 ABIN1536100 ELISA WB Rabbit IgG Cleaved-Asn120 Log in to see Polyclonal 3
2.9058776 ABIN1531644 IHC ELISA WB Rabbit IgG pSer376 Log in to see Polyclonal 3
2.9058776 ABIN252521 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468 24
2.9058776 ABIN222877 IF IP WB Rabbit IgG Log in to see Polyclonal 5
2.9058776 ABIN1532666 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 3
2.9058776 ABIN2862613 IHC ELISA WB Rabbit IgG AA 129-205, cleaved Log in to see Polyclonal
2.9058776 ABIN968350 IF WB Mouse IgG1 AA 47-168 Log in to see 35-p45 3
2.9058776 ABIN4288006 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 1
2.9058776 ABIN4287999 IHC IHC (p) WB Rabbit cleaved, full length Log in to see Polyclonal 1
2.9058776 ABIN3044293 IHC (p) WB Rabbit IgG AA 249-262, C-Term Log in to see Polyclonal 21
2.9058776 ABIN4288002 ICC IF IP WB Rabbit Log in to see Polyclonal 3
2.9058776 ABIN3183664 ELISA IHC WB Rabbit IgG Ser197 Log in to see Polyclonal
2.9058776 ABIN2654583 WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN3181758 ELISA IHC WB Rabbit IgG Asp210, cleaved Log in to see Polyclonal
2.9058776 ABIN2705671 IHC WB Rabbit Center Log in to see Polyclonal
2.9058776 ABIN2705672 IHC WB Rabbit Center Log in to see Polyclonal
2.9058776 ABIN2704574 IP IHC WB Rabbit C-Term Log in to see Polyclonal
2.9058776 ABIN560170 IHC (p) ELISA WB Mouse IgG2a kappa AA 1-100, partial Log in to see 3D2 2
2.9058776 ABIN4288024 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope Middle Region
(38), (15), (13), (12), (10), (9), (7), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Horse (Equine), Human, Rabbit, Yeast
(252), (94), (73), (8), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(235), (40), (8), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(18), (14), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(252), (138), (116), (84), (32), (26), (16), (6), (6), (5), (3), (3), (1)
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN974471
Sequence LQTRVLNKEE MEKVKRENAT VMDKTRALID SVIPKGAQAC QICITYICEE
Predicted Reactivity Horse: 79%, Human: 100%, Rabbit: 79%, Yeast: 100%
Characteristics This is a rabbit polyclonal antibody against CASP1. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CASP1

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CASP1 (CASP1 Antibody Abstract)
Background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
Alias Symbols: ICE, IL1BC, P45
Protein Interaction Partner: ced-3, ced-4, VAC14, BCL2L1, UBC, XK, PLA2G4B, IL33, IL1B, PARP1, BIRC3, TRAF2, CEBPB, TIRAP, CARD17, CARD16, CARD8, PLA2G4A, CDK11B, NLRP1, ATN1, ATXN3, PYCARD, NLRC4, NOD1, CASP14, RIPK2, PAK1, PARK2, NEDD4, BID, IL18, PSEN2, NFE2L2, AR, BCAP31, MAPT, L
Protein Size: 383
Molecular Weight 10 kDa
Gene ID 834
NCBI Accession NM_001223, NP_001214
UniProt P29466
Pathways Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 383 AA

Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (Middle Region) antibody (ABIN2787901) WB Suggested Anti-CASP1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500...