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anti-Human Caspase 1 antibody for Western Blotting

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • Ice
  • ICE
  • Il1bc
  • IL1BC
  • P45
  • CASP1
  • Death caspase-1
  • caspase-1
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-1-like
  • Dcp-1
  • Ice
  • AaeL_AAEL014348
  • Casp1
  • LOC100101588
  • CASP1
  • CASP4
  • LOC100725217
Epitope
pSer376
36
15
13
12
10
10
6
6
5
5
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
240
93
72
8
3
2
2
1
1
1
1
1
1
1
Host
Rabbit
224
39
8
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
18
14
7
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
241
132
111
80
30
23
15
6
6
5
3
3
1
Options
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Catalog No. ABIN1531644
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0882466 ABIN1536100 ELISA WB Rabbit IgG Cleaved-Asn120 Log in to see Polyclonal 3
3.0882466 ABIN222877 IF IP WB Rabbit IgG Log in to see Polyclonal 5
3.0882466 ABIN252521 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468 23
3.0882466 ABIN1532666 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 3
3.0882466 ABIN499541 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 1
3.0882466 ABIN499543 EIA IHC (p) WB Rabbit IgG Intermediate Domain Log in to see Polyclonal 4
3.0882466 ABIN4288006 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 1
3.0882466 ABIN968350 IF WB Mouse IgG1 AA 47-168 Log in to see 35-p45 3
3.0882466 ABIN4287999 IHC IHC (p) WB Rabbit cleaved, full length Log in to see Polyclonal 1
3.0882466 ABIN2787901 WB Rabbit Middle Region Log in to see Polyclonal
3.0882466 ABIN4288002 ICC IF IP WB Rabbit Log in to see Polyclonal 3
3.0882466 ABIN3044293 IHC (p) WB Rabbit IgG AA 249-262, C-Term Log in to see Polyclonal
3.0882466 ABIN3043221 IHC (p) WB Rabbit IgG AA 135-152, N-Term Log in to see Polyclonal
3.0882466 ABIN3183664 ELISA IHC WB Rabbit IgG Ser197 Log in to see Polyclonal
3.0882466 ABIN3181758 ELISA IHC WB Rabbit IgG Asp210, cleaved Log in to see Polyclonal
3.0882466 ABIN2705672 IHC WB Rabbit Center Log in to see Polyclonal
3.0882466 ABIN2705671 IHC WB Rabbit Center Log in to see Polyclonal
3.0882466 ABIN2704574 IP IHC WB Rabbit C-Term Log in to see Polyclonal
3.0882466 ABIN560170 IHC (p) ELISA WB Mouse IgG2a kappa AA 1-100, partial Log in to see 3D2 2
3.0882466 ABIN2855008 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal

Top referenced anti-Caspase 1 antibody for Western Blotting

Similar anti-Caspase 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 16 Antibodies 19 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 7 Antibodies
Immunofluorescence (IF) 11 Antibodies 12 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 42 Antibodies 48 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antibodies 36 Antibodies
Immunoprecipitation (IP) 13 Antibodies 15 Antibodies
Simple Western (SimWes) 3 Antibodies
Western Blotting (WB) 70 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 6 Antibodies

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope pSer376
(36), (15), (13), (12), (10), (10), (6), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(240), (93), (72), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(224), (39), (8), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(18), (14), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(241), (132), (111), (80), (30), (23), (15), (6), (6), (5), (3), (3), (1)
Pubmed 3 references available
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN1531644) Images
Specificity Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.
Isotype IgG

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 Antibody (ABIN1531644) Images back to top
Antigen
Alternative Name Caspase 1 (CASP1 Antibody Abstract)
Background Molecular weight of target protein: 29 kDa
Synonyms: CASP-1, caspase-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45
Molecular Weight 29 kDa
Gene ID 834
OMIM 147678
UniProt P29466
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 Antibody (ABIN1531644) Images back to top
Application Notes WB: 1:500-1:1000
IHC: 1:50-1:100
ELISA: 1:20000
Optimal working dilution should be determined by the investigator.
Comment

Unigene-Number: Hs.2490 (NCBI Gene Symbol: CASP1)

Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 Antibody (ABIN1531644) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 52 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20 °C for at least 1 year.
Expiry Date 12 months

References for anti-Caspase 1 Antibody (ABIN1531644)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Background publications

Feng, Li, Leung, Auersperg: "Caspase-1zeta, a new splice variant of the caspase-1 gene." in: Genomics, Vol. 84, Issue 3, pp. 587-91, 2004

Agostini, Martinon, Burns, McDermott, Hawkins, Tschopp: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004

Thornberry, Bull, Calaycay, Chapman, Howard, Kostura, Miller, Molineaux, Weidner, Aunins: "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes." in: Nature, Vol. 356, Issue 6372, pp. 768-74, 1992

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN1531644) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 antibody (CASP1) (pSer376) (ABIN1531644) Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) An...
Immunohistochemistry (IHC) image for anti-Caspase 1 antibody (CASP1) (pSer376) (ABIN1531644) Immunohistochemistry analysis of paraffin-embedded human brain, using Caspase 1 (Phos...