anti-Rat (Rattus) Caspase 1 antibody for Western Blotting

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 1
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1-like
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Ice
  • AaeL_AAEL014348
  • LOC100725217
  • LOC100101588
Epitope
AA 342-391, pSer376
38
15
13
12
10
10
7
6
6
5
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
253
93
73
8
3
2
2
1
1
1
1
1
1
1
Host
Rabbit
236
40
8
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
18
14
7
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
253
137
116
84
32
26
16
6
6
5
3
3
1
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Catalog No. ABIN1531644
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2214506 ABIN1532666 IHC ELISA WB Rabbit IgG AA 342-391 Log in to see Polyclonal 3
3.2214506 ABIN252521 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468 24
3.2214506 ABIN222877 IF IP WB Rabbit IgG Log in to see Polyclonal 5
3.2214506 ABIN968350 IF WB Mouse IgG1 AA 47-168 Log in to see 35-p45 3
3.2214506 ABIN4288002 ICC IF IP WB Rabbit Log in to see Polyclonal 3
3.2214506 ABIN3183664 ELISA IHC WB Rabbit IgG Ser197 Log in to see Polyclonal
3.2214506 ABIN4288024 IHC IHC (p) SimWes WB Mouse IgG1 kappa Log in to see 14F468
3.2214506 ABIN2705671 IHC WB Rabbit Center Log in to see Polyclonal
3.2214506 ABIN3021171 IHC WB Rabbit IgG Log in to see Polyclonal
3.2214506 ABIN1174809 ICC IHC IP WB Rabbit IgG AA 119-296 Log in to see Polyclonal
3.2214506 ABIN3030287 WB Rabbit IgG N-Term, Subunit p20 Log in to see Polyclonal
3.2214506 ABIN2403696 IHC WB Rabbit IgG Log in to see Polyclonal
3.2214506 ABIN2427583 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN115380 IHC (p) WB Rabbit Log in to see Polyclonal 4
1 ABIN115381 IHC (p) WB Rabbit Log in to see Polyclonal 2
1 ABIN5518669 WB Rabbit IgG AA 137-157, N-Term Log in to see Polyclonal 21
1 ABIN126963 IF IP WB Rabbit Log in to see Polyclonal
1 ABIN5611451 IHC (p) IP WB Rabbit Log in to see Polyclonal
1 ABIN2888870 IHC (p) ELISA WB Rabbit IgG AA 342-391 Log in to see Polyclonal
1 ABIN3182631 ELISA IHC WB Rabbit IgG pSer376 Log in to see Polyclonal

General

Antigen Caspase 1 (CASP1) Antibodies
Epitope AA 342-391, pSer376
(38), (15), (13), (12), (10), (10), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(253), (93), (73), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(236), (40), (8), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(18), (14), (7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(253), (137), (116), (84), (32), (26), (16), (6), (6), (5), (3), (3), (1)
Pubmed 3 references available
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) Images
Specificity

Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.

PhosphorylationH:S376 M:S374 R:S374

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.
Isotype IgG

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Antigen
Alternative Name Caspase 1 (CASP1 Antibody Abstract)
Background

Synonyms: CASP-1, caspase-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

NCBI Gene Symbol: CASP1

Molecular Weight 29 kDa
Gene ID 834
OMIM 147678
UniProt P29466
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Application Notes WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
Comment

Unigene-Number: Hs.2490 (NCBI Gene Symbol: CASP1)

Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 antibody (ABIN1531644) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months

References for anti-Caspase 1 antibody (ABIN1531644)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Background publications

Feng, Li, Leung, Auersperg: "Caspase-1zeta, a new splice variant of the caspase-1 gene." in: Genomics, Vol. 84, Issue 3, pp. 587-91, 2004

Agostini, Martinon, Burns, McDermott, Hawkins, Tschopp: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004

Thornberry, Bull, Calaycay, Chapman, Howard, Kostura, Miller, Molineaux, Weidner, Aunins: "A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes." in: Nature, Vol. 356, Issue 6372, pp. 768-74, 1992

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 antibody (ABIN1531644) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 (CASP1) (pSer376), (AA 342-391) antibody (ABIN1531644) Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) An...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) (pSer376), (AA 342-391) antibody (ABIN1531644) Immunohistochemistry analysis of paraffin-embedded human brain, using Caspase 1 (Phos...