Browse our Caspase 1 (CASP1) ELISA Kits

On are 57 Caspase 1 (CASP1) ELISA Kits from 16 different suppliers available. Additionally we are shipping Caspase 1 Antibodies (280) and Caspase 1 Proteins (35) and many more products for this protein. A total of 393 Caspase 1 products are currently listed.
CASP1, ccp1, CG5370, dcp-1, dcp1, Dmel\\CG5370, Ice, Il1bc, l(2)01862, l(2)02132, P45
list all ELISA KIts Gene Name GeneID UniProt
CASP1 834 P29466
CASP1 12362 P29452
CASP1 25166  

Caspase 1 (CASP1) ELISA Kits by Reactivity

More ELISA Kits for Caspase 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Caspase 1 (CASP1) interaction partners

  1. drICE (show CASP3 ELISA Kits) and dcp-1 (show ACE ELISA Kits) function in cell death redundantly. However, dying neurons in a few clusters strictly required drICE (show CASP3 ELISA Kits) but not dcp-1 (show ACE ELISA Kits), but required drICE (show CASP3 ELISA Kits) and dcp-1 (show ACE ELISA Kits) when drICE (show CASP3 ELISA Kits) activity was reduced via hypomorphic mutation.

  2. Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1 (show ACE ELISA Kits), and ice

  3. Autophagy suppresses Dcp-1 (show ACE ELISA Kits)-mediated apoptotic cell death, whereas Dcp-1 (show ACE ELISA Kits) positively regulates autophagy, possibly through feedback regulation.

  4. novel characteristic morphological features of egg chambers lacking both dcp-1 (show ACE ELISA Kits) and pita functions in the germline cells; suggested an essential role of dcp-1 (show ACE ELISA Kits) and/or pita during mid-oogenesis

  5. A double-mutant analysis between drICE (show CASP3 ELISA Kits) and death caspase-1 (dcp-1), another effector caspase (show CASP3 ELISA Kits), reveals that some cells (type I) strictly require drICE (show CASP3 ELISA Kits) for apoptosis, whereas other cells (type II) require either drICE (show CASP3 ELISA Kits) or dcp-1 (show ACE ELISA Kits).

  6. Data show that the effector caspase Dcp-1 and the inhibitor of apoptosis protein (show BIRC2 ELISA Kits) Bruce (show BIRC6 ELISA Kits) function to regulate both autophagy and starvation-induced cell death in Drosophila.

  7. HeT-A mRNA is derepressed in mRNA degradation mutants dcp1 (show ACE ELISA Kits), indicating that the enzyme also aid in removing full-length transcripts and/or decay intermediates.

Silk Worm Caspase 1 (CASP1) interaction partners

  1. cBm-IAP1 (show BIRC3 ELISA Kits) is a vital negative regulator of apoptosis in BM-N cells and functions by preventing the activation and/or activity of Bm-Dronc and Bm-caspase-1.

  2. Activation of Atg5 (show ATG5 ELISA Kits), AIF (show AIFM1 ELISA Kits) and caspase (show CASP3 ELISA Kits) genes in close association with different cell death events revealed the synchronized differential expression of apoptosis-associated genes in response to macroparasitism.

Mouse (Murine) Caspase 1 (CASP1) interaction partners

  1. The most well-known function of active caspase-1 is to cleave the proforms of inflammatory cytokines IL-1beta (show IL1B ELISA Kits) and -18 into their active forms in response to inflammatory stimuli in immune cells. Caspase-1 has multiple functions in addition to this cytokine maturation role. It is at the center of many cell responses to stress and inflammation not just in immune cells but in other cell types, such as epithelia. Review.

  2. Findings demonstrate a critical role of caspase-1 in macrophage-driven inflammation in the adipose tissue and the development of obesity.

  3. Inflammasome NLRP3 (show NLRP3 ELISA Kits)-caspase-1-mediated degradation of smooth muscle cell contractile proteins may contribute to aortic biomechanical dysfunction and aortic aneurysm/dissection development.

  4. Data indicate that NLRC4 (show NLRC4 ELISA Kits) activation in Intestinal epithelial cells (IECs) leads to cell expulsion and IL-18 (show IL18 ELISA Kits) release, and implicate Caspase-8 (show CASP8 ELISA Kits) in NLRC4 (show NLRC4 ELISA Kits) inflammasome responses in vivo by generation of doubly deficient in Caspase-1 and Caspase-8 (show CASP8 ELISA Kits).

  5. our studies have uncovered a specific role for caspase-1-mediated IL-1beta (show IL1B ELISA Kits) release in the manifestation of Familial Mediterranean Fever (show MEFV ELISA Kits)

  6. variant p.C284A caspase-1 stabilizes pyroptosome formation, potentially enhancing inflammation by two IL-1beta (show IL1B ELISA Kits)-independent mechanisms: pyroptosomes convey an enhanced inflammatory stimulus through the recruitment of additional proteins (such as RIP2 (show ARHGDIG ELISA Kits), receptor interacting protein (show RIPK1 ELISA Kits) kinase 2 (show PKC ELISA Kits)), which is further amplified through pyroptosome and cell division.

  7. TNF-alpha (show TNF ELISA Kits) induces caspase-1 activation in an inflammasome-independent manner in 3T3-L1 cells and that the ERK (show EPHB2 ELISA Kits)-dependent expression of NLRP3 (show NLRP3 ELISA Kits) may play a role independently of its canonical role as a component of inflammasomes.

  8. caspase-1 activation is an upstream event of apoptotic caspase-7 (show CASP7 ELISA Kits) induction in renal tubulointerstitial fibrosis

  9. it was found that GSK2656157 specifically inhibited ER stress induced by large amount of LPS (show TLR4 ELISA Kits) and reduced LPS (show TLR4 ELISA Kits)-induced IL-1beta (show IL1B ELISA Kits) production through inhibition of Caspase 1 activation.

  10. Study suggests that Casp1 has a limited role in the development of burn-induced pain.

Human Caspase 1 (CASP1) interaction partners

  1. Proteases caspase-1 and caspase-8 (show CASP8 ELISA Kits) have redundant roles in cleaving IL-1beta (show IL1B ELISA Kits) and promoting osteomyelitis. [review]

  2. Patients with NLRP1 (show NLRP1 ELISA Kits)-associated autoinflammation with arthritis and dyskeratosis syndrome had increased systemic CASP1.

  3. The biochemical function of NLPR3 inflammasomes is to activate caspase-1, which leads to the maturation of interleukin 1 beta (show IL1B ELISA Kits) and IL-18 (show IL18 ELISA Kits) and the induction of pyroptosis, a form of cell death. (Review)

  4. The structure of the human caspase-1 CARD domain (caspase-1(CARD)) filament solved by cryo-electron microscopy.

  5. Caspase-1-mediated downregulation of PPARgamma (show PPARG ELISA Kits) was important in the late stage of monocyte-macrophage differentiation; however, PPARgamma (show PPARG ELISA Kits) protein levels had little effect on the early stage differentiation.

  6. Inflammasome NLRP3 (show NLRP3 ELISA Kits)-caspase-1-mediated degradation of smooth muscle cell contractile proteins may contribute to aortic biomechanical dysfunction and aortic aneurysm/dissection development.

  7. Study demonstrates that the expression of the NLRP3 (show NLRP3 ELISA Kits)-caspase-1-IL-18 (show IL18 ELISA Kits) axis is highly expressed in the peripheral blood mononuclear cells of patients with bullous pemphigoid (show DST ELISA Kits) (BP), and correlated with disease activity, suggesting its involvement in the pathogenesis and progression of BP.

  8. High expression of CASP1 is associated with osteosarcoma.

  9. This study demonstrated that dysregulated expression of NLRP3 (show NLRP3 ELISA Kits)-caspase-1-IL-1beta (show IL1B ELISA Kits) axis was observed in patients with MM, suggesting they might be involved in the pathogenesis of MM.

  10. The NLRP3 (show NLRP3 ELISA Kits)/caspase-1/IL-1beta (show IL1B ELISA Kits) axis is active in cartilaginous endplates of patients with Modic changes and inflammatory cascades can exacerbate the cartilaginous endplate degeneration which may act as a trigger for intervertebral disc degeneration and low back pain.

Pig (Porcine) Caspase 1 (CASP1) interaction partners

  1. Src kinase (show CSK ELISA Kits) mediates hypoxia-induced caspase-1 activation in the cerebral cortex of newborn piglets

  2. endometrial expression of CASP1 and IL18 (show IL18 ELISA Kits) associated with pregnancy establishment; alteration of CASP1 and IL18 (show IL18 ELISA Kits) following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy

Caspase 1 (CASP1) Antigen Profile

Antigen Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 1 (CASP1)

  • caspase 1, apoptosis-related cysteine peptidase (CASP1) Elisa Kit
  • caspase 1 (Casp1) Elisa Kit
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) Elisa Kit
  • Death caspase-1 (Dcp-1) Elisa Kit
  • caspase-1 (Ice) Elisa Kit
  • caspase-1 (AaeL_AAEL014348) Elisa Kit
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (CASP1) Elisa Kit
  • caspase-1-like (LOC100725217) Elisa Kit
  • caspase 1 (LOC100101588) Elisa Kit
  • CASP1 Elisa Kit
  • ccp1 Elisa Kit
  • CG5370 Elisa Kit
  • dcp-1 Elisa Kit
  • dcp1 Elisa Kit
  • Dmel\\CG5370 Elisa Kit
  • Ice Elisa Kit
  • Il1bc Elisa Kit
  • l(2)01862 Elisa Kit
  • l(2)02132 Elisa Kit
  • P45 Elisa Kit

Protein level used designations for Caspase 1 (CASP1) ELISA Kits

CASP1 nirs variant 1 , IL-1 beta-converting enzyme , IL1B-convertase , caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) , caspase-1 , interleukin 1, beta, convertase , interleukin 1-B converting enzyme , CASP-1 , IL-1B converting enzyme , IL-1BC , interleukin 1 beta-converting enzyme , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , Interleukin 1beta converting enzyme , caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) , ICE , interleukin-1 beta converting enzyme , caspase-1/caspase-4 hybrid , CG5370-PA , Dcp-1-PA , caspase , caspase 1 , death caspase-1

834 Homo sapiens
12362 Mus musculus
25166 Rattus norvegicus
395764 Gallus gallus
397319 Sus scrofa
403724 Canis lupus familiaris
37729 Drosophila melanogaster
692604 Bombyx mori
5564196 Aedes aegypti
100033888 Equus caballus
451519 Pan troglodytes
514214 Bos taurus
100437679 Pongo abelii
100588974 Nomascus leucogenys
706568 Macaca mulatta
100725217 Cavia porcellus
100101588 Oryctolagus cuniculus
493961 Felis catus
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