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anti-Human Caspase 10 antibody for Intracellular Flow Cytometry

Recommended Caspase 10 Antibody (supplied by: Log in to see )

Antigen
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
  • alps2
  • ALPS2
  • caspace-10
  • caspase-10
  • FLICE2
  • flice2
  • MCH4
  • mch4
  • xCaspace-10
  • xCaspase-10
Reactivity
Human, Mouse (Murine)
138
19
18
1
Host
Rat
124
9
2
2
1
Clonality
Monoclonal
Conjugate
This Caspase 10 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Intracellular Flow Cytometry (ICFC)
110
45
32
21
19
11
8
7
3
2
2
1
Supplier
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Catalog No. ABIN2666064
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Top referenced anti-Caspase 10 antibody for Intracellular Flow Cytometry

Similar anti-Caspase 10 Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 112 Antibodies 18 Antibodies
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Intracellular Flow Cytometry (ICFC) 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 8 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 34 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunofluorescence (IF) 23 Antibodies 5 Antibodies
Immunocytochemistry (ICC) 10 Antibodies 3 Antibodies
Immunochromatography (IC) 2 Antibodies 1 Antibodies

General

Antigen Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
Reactivity Human, Mouse (Murine)
(138), (19), (18), (1)
Host Rat
(124), (9), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 10 antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Intracellular Flow Cytometry (ICFC)
(110), (45), (32), (21), (19), (11), (8), (7), (3), (2), (2), (1)
Pubmed 2 references available
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Product Details anti-Caspase 10 Antibody

Target Details Caspase 10 Application Details Handling References for anti-Caspase 10 Antibody (ABIN2666064) Images
Purification The antibody was purified by affinity chromatography.
Clone 25C2
Isotype IgG2a

Target Details Caspase 10

Product Details anti-Caspase 10 Antibody Application Details Handling References for anti-Caspase 10 Antibody (ABIN2666064) Images back to top
Antigen
Alternative Name Caspase-10 (CASP10 Antibody Abstract)
Background There are two types of apoptotic caspases, initiator (apical) caspases and effector (executioner) caspases. Caspase 10 is one of the initiator caspases that cleave inactive pro-forms of effector caspases, thereby activating them. Four isoforms, namely Caspase-10a,-10 b,-10c,and -10d have been identified. They derived from a single chain polypeptide proenzyme but have different mature large and small subunits by cleavage. After the death ligand-receptor binding, caspade-10 has joined the multimeric Fas/TNF receptor complex and gets cleaved. The cleaved caspase-10 further acts on other effector caspases to initiate the caspase cascade.
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Handling References for anti-Caspase 10 Antibody (ABIN2666064) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details References for anti-Caspase 10 Antibody (ABIN2666064) Images back to top
Concentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Upon receipt, store between 2°C and 8°C.

References for anti-Caspase 10 Antibody (ABIN2666064)

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Handling Images back to top
Background publications

Ng, Porter, Jänicke: "Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10301-8, 1999

Cohen: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, 1997

Images

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Handling References for anti-Caspase 10 Antibody (ABIN2666064) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 10 antibody (Caspase 10, Apoptosis-Related Cysteine Peptidase) (ABIN2666064) anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibody