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anti-Human Caspase 10 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Caspase 10 Antibody (supplied by: Log in to see )

Antigen
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
  • alps2
  • ALPS2
  • caspace-10
  • caspase-10
  • FLICE2
  • flice2
  • MCH4
  • mch4
  • xCaspace-10
  • xCaspase-10
Reactivity
Human
138
20
18
1
Host
Rabbit
123
9
3
2
1
Clonality
Polyclonal
Conjugate
This Caspase 10 antibody is conjugated to Alexa Fluor 350
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
110
45
32
21
19
10
8
7
3
2
2
1
1
Supplier
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Catalog No. ABIN886662
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008837127 ABIN886665 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN886666 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN886663 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724778 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724779 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724780 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724781 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724782 IF (p) FITC Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN2811136 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
0.0008837127 ABIN724775 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-Caspase 10 Antibodies

Application / Reactivity Human
ELISA 45 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 10 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 34 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 112 Antibodies

General

Antigen Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) Antibodies
Reactivity Human
(138), (20), (18), (1)
Host Rabbit
(123), (9), (3), (2), (1)
Clonality
Polyclonal
Conjugate This Caspase 10 antibody is conjugated to Alexa Fluor 350
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(110), (45), (32), (21), (19), (10), (8), (7), (3), (2), (2), (1), (1)
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Product Details anti-Caspase 10 Antibody

Target Details Caspase 10 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Caspase-10
Isotype IgG

Target Details Caspase 10

Product Details anti-Caspase 10 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-10 (CASP10 Antibody Abstract)
Background

Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.

Subcellular location: Secreted


Synonyms: ALPS 2, ALPS2, Apoptosis related cysteine peptidase, Apoptotic protease Mch 4, CASP 10, CASP10, CASP10 protein, Caspase 10 apoptosis related cysteine peptidase, Caspase 10 apoptosis related cysteine protease, Caspase10, FADD Like Ice 2, Fas Associated Death Domain Protein, FAS associated death domain protein interleukin 1B converting enzyme 2, FLICE 2, FLICE2, ICE Like Apoptotic Protease 4, Interleukin 1B Converting Enzyme 2, MCH 4, MCH4.
Gene ID 843
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Handling Images back to top
Application Notes IF(IHC-P)(1:50-200)
Comment

Exitation/Emission: 343nm/442nm

Restrictions For Research Use only

Handling

Product Details anti-Caspase 10 Antibody Target Details Caspase 10 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months