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anti-Human Caspase 2 antibody for Immunocytochemistry

Recommended Caspase 2 Antibody (supplied by: Log in to see )

Antigen
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
  • xCaspase-2
  • Caspase-2
  • ICH-1
  • Nedd2
  • CASP-2
  • ICH1
  • NEDD-2
  • NEDD2
  • PPP1R57
  • ICH-1L/1S
  • ICH1L1S
  • caspase-2-like
  • caspase-2
  • caspase 2
  • caspase 2, apoptosis-related cysteine peptidase
  • LOC100050611
  • xCaspase-2
  • CpipJ_CPIJ008254
  • Casp2
  • LOC100101590
  • CASP2
  • LOC100521118
Epitope
N-Term
27
20
14
9
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
204
87
67
8
6
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
153
51
10
Clonality
Polyclonal
Conjugate
This Caspase 2 antibody is un-conjugated
6
6
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
175
94
45
33
14
14
13
11
10
4
4
4
2
1
Supplier
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Supplier Product No.
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Catalog No. ABIN1002005
$ 466.62
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN214432 ICC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1077908 ICC IHC IP WB Rabbit IgG AA 334-452 Log in to see Polyclonal
1 ABIN4957588 ELISA ICC IF WB Rabbit N-Term Log in to see Polyclonal
1 ABIN4288067 ICC IF IHC IHC (p) Rabbit Log in to see Polyclonal
1 ABIN4288071 ELISA ICC IF WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1031296 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN4903136 FACS ICC IF IHC WB Rabbit IgG Log in to see
1 ABIN198454 ICC FACS IHC (fro) ELISA Rat IgG2a Log in to see
1 ABIN2617929 ICC IHC (fro) FACS ELISA Rat IgG2a, kappa Log in to see 10C6
1 ABIN1887986 ICC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1732648 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN1583603 ICC ELISA WB Rabbit Log in to see Polyclonal
1 ABIN1172666 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal

Top referenced anti-Caspase 2 antibody for Immunocytochemistry

Similar anti-Caspase 2 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 22 Antibodies 91 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Flow Cytometry (FACS) 5 Antibodies 10 Antibodies
Immunocytochemistry (ICC) 12 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 17 Antibodies
Immunoprecipitation (IP) 9 Antibodies
Western Blotting (WB) 68 Antibodies
BioImaging (BI) 1 Antibodies
Immunochromatography (IC) 4 Antibodies

General

Antigen Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) Antibodies
Epitope N-Term
(27), (20), (14), (9), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(204), (87), (67), (8), (6), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(153), (51), (10)
Clonality
Polyclonal
Conjugate This Caspase 2 antibody is un-conjugated
(6), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(175), (94), (45), (33), (14), (14), (13), (11), (10), (4), (4), (4), (2), (1)
Pubmed 4 references available
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Product Details anti-Caspase 2 Antibody

Target Details Caspase 2 Application Details Handling References for anti-Caspase 2 Antibody (ABIN1002005) Images
Blocking Peptide Blocking peptide for this product available: ABIN1004107
Purification Affinity chromatography purified via peptide column.
Immunogen Rabbit polyclol caspase-2 antibody was raised against a 16 amino acid peptide from the amino-terminus of human caspase-2 (Genbank accession No. P42575).
Isotype IgG

Target Details Caspase 2

Product Details anti-Caspase 2 Antibody Application Details Handling References for anti-Caspase 2 Antibody (ABIN1002005) Images back to top
Antigen
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1beta and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms, overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
Pathways Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Handling References for anti-Caspase 2 Antibody (ABIN1002005) Images back to top
Application Notes Caspase-2 antibody can be used for the detection of caspase-2 by Western blot at 1 µg/ml. (Optimal dilution should be determined by user.) Depending on cell lines or tissues used, other cleavage products may be observed. Antibody can also be used for immunocytochemistry and ELISA and might be suited for other applications not tested so far.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details References for anti-Caspase 2 Antibody (ABIN1002005) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-Caspase 2 Antibody (ABIN1002005)

Product Details anti-Caspase 2 Antibody Target Details Caspase 2 Application Details Handling Images back to top
Background publications

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004

Gracie, Robertson, McInnes: "Interleukin-18." in: Journal of leukocyte biology, Vol. 73, Issue 2, pp. 213-24, 2003

Kuida, Lippke, Ku, Harding, Livingston, Su, Flavell: "Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme." in: Science (New York, N.Y.), Vol. 267, Issue 5206, pp. 2000-3, 1995