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Browse our Caspase 3 (CASP3) ELISA Kits

Full name:
Caspase 3, Apoptosis-Related Cysteine Peptidase ELISA Kits (CASP3)
On www.antibodies-online.com are 93 Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) ELISA Kits from 18 different suppliers available. Additionally we are shipping Caspase 3 Antibodies (629) and Caspase 3 Proteins (44) and many more products for this protein. A total of 821 Caspase 3 products are currently listed.
Synonyms:
A830040C14Rik, AC-3, Apopain, Cas3, Casp 3, Casp3, caspase-3, caspase 3, CC3, CG7788, CG14902, CPP32, CPP32B, crice, Decay, Dmel\\CG7788, Dmel\\CG14902, drice, Drosophila executioner caspase related to Apopain/Yama, ice, Lice, mldy, SCA-1, xcpp32, Yama
list all ELISA KIts Gene Name GeneID UniProt
CASP3 12367 P70677
CASP3 25402 P55213
CASP3 836 P42574

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Top referenced Caspase 3 ELISA Kits

  1. ABIN411828 : Defaux, Zurich, Honegger, Monnet-Tschudi: Inflammatory responses in aggregating rat brain cell cultures subjected to different demyelinating conditions. in Brain research 2010 (PubMed)
    Show all 99 references for ABIN411828

  2. ABIN411824 : Lian, Wu, He, Karnak, Tang, Meng, Xiang, Ji, Lawrence, Xu: A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. in Cell death and differentiation 2010 (PubMed)
    Show all 55 references for ABIN411824

  3. Rat (Rattus) Caspase 3 ELISA Kit for Sandwich ELISA - ABIN811984 : Em, Ar, Am, Aa: Thymol and Carvacrol Prevent Cisplatin-Induced Nephrotoxicity by Abrogation of Oxidative Stress, Inflammation, and Apoptosis in Rats. in Journal of biochemical and molecular toxicology 2015 (PubMed)
    Show all 6 references for ABIN811984

  4. Mouse (Murine) Caspase 3 ELISA Kit for Sandwich ELISA - ABIN415402 : Zobeiri, Salami, Sadrkhanlou, Peirouvi: Role of mitochondria in ciprofloxacin-induced apoptosis in murine sperm cells. in Reproductive sciences (Thousand Oaks, Calif.) 2013 (PubMed)
    Show all 5 references for ABIN415402

  5. Human Caspase 3 ELISA Kit for Sandwich ELISA - ABIN811983 : Li, Zhou, Jiang, He, Jia, Zhao, Cheng, Jia: PEGylated VRB plus quinacrine cationic liposomes for treating non-small cell lung cancer. in Journal of drug targeting 2014 (PubMed)

  6. Rabbit Caspase 3 ELISA Kit for Sandwich ELISA - ABIN832429 : Kertmen, Gürer, Y?lmaz, Sanl?, Sorar, Ar?kök, Sargon, Kanat, Ergüder, Sekerci: The protective effect of low-dose methotrexate on ischemia-reperfusion injury of the rabbit spinal cord. in European journal of pharmacology 2013 (PubMed)

More ELISA Kits for Caspase 3 Interaction Partners

Fruit Fly (Drosophila melanogaster) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila.

  2. drICE plays an important role in activating corpse clearance in dying cells, and that an additional function of effector caspases is required for the activation of corpse clearance as well as that for carrying out cell death.

  3. Both autophagy and caspase activity are induced by 20-hydroxyecdysone during the larval-prepupal transition.

  4. The cleaved DIAP1 (show DIAPH1 ELISA Kits) binds drICE, inhibits its protease activity, and also targets drICE for ubiquitylation.

  5. Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1 (show ACE ELISA Kits), and ice

  6. Data suggest that the cleaved-Caspase-3 antibody recognizes multiple proteins including DCP-1 (show ACE ELISA Kits) and likely DRICE, but also at least one additional unknown protein, all of which require DRONC for epitope exposure.

  7. The caspase effector DRICE is activated during apoptosis in both mid- and late oogenesis; however, active DRICE was found more ubiquitously and at a higher level during germline cell death in midoogenesis.

  8. examination of inhibition by DIAP1 (show DIAPH1 ELISA Kits)

  9. Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells.

  10. A double-mutant analysis between drICE and death caspase-1 (dcp-1), another effector caspase, reveals that some cells (type I) strictly require drICE for apoptosis, whereas other cells (type II) require either drICE or dcp-1 (show ACE ELISA Kits).

Mouse (Murine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. These studies suggest a link between Bik (show BIK ELISA Kits)-mediated caspase activation and cleavage of viral proteins.

  2. melatonin could inhibit TLR4 (show TLR4 ELISA Kits) expression in hypoxic microglia followed by suppression of caspase3 activation leading to decrease in production of proinflammatory mediators

  3. A significant emergence of GFP-expressing PCs and interneurons in symptomatic, but not non-symptomatic, SCA1 (show ATXN1 ELISA Kits) mice 2 weeks after the MSC (show MSC ELISA Kits) injection.

  4. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (show AKT1 ELISA Kits)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (show AKT1 ELISA Kits) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

  5. cognitive decline was significantly correlated with increased levels of caspase activity and tau truncated by caspase-3

  6. this study shows that Le Carbone, a charcoal supplement, attenuates experimental colitis through caspase 3 dependent apoptotic pathways

  7. Cepharanthine treatment reduced mitochondrial membrane potential and upregulated the level of cleaved caspases, including caspase-9 (show CASP9 ELISA Kits) and caspase-3/7, in a dose-dependent fashion.

  8. Our results showed that Sca-1 (show Ly6a ELISA Kits)(+) MSCs inhibit the commitment of marginal zone B lymphocytes. The inhibition was exerted through lowered Caspase-3 expression. Furthermore, we found marginal zone B lymphocytes in spleen of Caspase-3 knockout mice decreased and Caspase-3 knockout Sca-1 (show Ly6a ELISA Kits)(+) MSCs accounted for the MZB lymphocytes decrease.

  9. caspase-3 is essential for a subset of social behaviors, but despite similar hyper-locomotion in both sexes, only male Casp3(-/-) mice exhibited social interaction deficits, which is interesting given the male bias of autism

  10. Study identified CASP-3 mRNA as a new miRNA-155 target in lipopolysaccharides-activated macrophages suggesting that through destabilization of CASP-3, miR (show MLXIP ELISA Kits)-155 contributes to the protective role to sustain macrophage function in inflammation response.

Human Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. These studies suggest a link between Bik (show BIK ELISA Kits)-mediated caspase activation and cleavage of viral proteins.

  2. High levels of FADD (show FADD ELISA Kits) and caspase-8 (show CASP8 ELISA Kits), but not caspase-3, were associated with increased incidence of coronary events in subjects from the general population.

  3. Interestingly, EspC-induced apoptosis was triggered through a dual mechanism involving both independent and dependent functions of its EspC serine protease (show F2 ELISA Kits) motif, the direct cleavage of procaspase-3 being dependent on this motif.

  4. LRRC8A (show LRRC8A ELISA Kits) is an essential regulator of cisplatin induced p53 (show TP53 ELISA Kits) protein activity and its downstream signaling involving increased expression of p21Waf1/Cip1 and MDM2 (show MDM2 ELISA Kits), as well as activation of caspase-9 (show CASP9 ELISA Kits) and -3 in tumor cell lines.

  5. Our results provide evidence that inhibition of the denitrosylation of S-nitrosylated procaspase-3 mediated by the redox protein Trx2 is a part of the microglial pro-tumoral activation pathway initiated by glioma cancer cells.

  6. These results highlight apoptosis-related CASP3 as an important gene in human carcinogenesis and further support the CASP3 polymorphisms confer to the lung cancer susceptibility.

  7. These findings revealed that rs4647693 G/A, rs4647610 A/G, and rs12108497 T/C polymorphisms of Caspase-3 may be associated with susceptibility to intervertebral disc herniation.

  8. the present study demonstrated that DAPK (show DAPK1 ELISA Kits) contributed to the Hcyinduced endothelial apoptosis via modulation of Bcl2 (show BCL2 ELISA Kits)/Bax (show BAX ELISA Kits) expression levels and activation of caspase 3

  9. Data show that the apoptotic and cytotoxic effects of BL-038 are mediated by the intrinsic mitochondria-mediated apoptotic pathway, which in turn causes the activation of caspase-9 (show CASP9 ELISA Kits) and caspase-3, and the cleavage of poly (ADP-ribose) polymerase (PARP (show PARP1 ELISA Kits)), to elicit apoptosis response.

  10. Data show that MeCP2 (show MECP2 ELISA Kits) promotes gastric cancer (GC) cell proliferation via FOXF1 (show FOXF1 ELISA Kits)-mediated Wnt5a (show WNT5A ELISA Kits)/beta-Catenin (show CTNNB1 ELISA Kits) signaling pathway, and suppresses GC cell apoptosis through MYOD1 (show MYOD1 ELISA Kits)-mediated Caspase-3 signaling pathway.

Cow (Bovine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Over-expression of STC-1 (show STC1 ELISA Kits) up-regulated Bcl-2 (show BCL2 ELISA Kits) protein expression and slightly down-regulated caspase-3 production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 ELISA Kits) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. Data suggest that Escherichia coli infections (here, administration of LPS (show IRF6 ELISA Kits)) provokes luteolysis in diestrus, non-lactating cows and up-regulation of expression of caspase 3 in corpus luteum but has no effect on luteinization in the following cycle.

  3. Data suggest that activation of caspase-3 is likely involved in both spontaneous and induced apoptosis in bovine pre-implantation embryos.

  4. mRNA expression of Bax (show BAX ELISA Kits), Bcl-2 (show BCL2 ELISA Kits), caspase-3 and-7 cannot be used as a reliable apoptosis detection method.

  5. the capacity for blastocysts to undergo further development is related to degree of group II caspase activity

  6. Treatment of mammary epithelial cells with serotonin 1B and serotonin 2A receptor antagonists increased caspase-3 activity.

Pig (Porcine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. This study demonstrated that LAMPs from M. hyopneumoniae can induce apoptosis in St. Jude porcine lung epithelial cell line through the activation of caspase 3, caspase 8 (show CASP8 ELISA Kits), cyt c (show CYCS ELISA Kits), Bax (show BAX ELISA Kits), and p38 MAPK (show MAPK14 ELISA Kits).

  2. Caspase-3 (CC3) was shown to be more abundant in early-cleaving and more developmentally competent embryos compared to late-cleaving and less developmentally competent embryos.

  3. Results suggest that zearalenone induces apoptosis and necrosis of porcine granulosa cells in a dose-dependent manner via a caspase-3- and caspase-9 (show CASP9 ELISA Kits)-dependent mitochondrial pathway.

  4. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (show MMP9 ELISA Kits) and MMP-2 (show MMP2 ELISA Kits), caspase-3 and BDNF (show BDNF ELISA Kits)

  5. both caspase-3-dependent and -independent pathways of programmed cell death increased upon Salmonella typhimurium infection.

  6. clonidine administration prior to hypoxia prevents the hypoxia-induced increase in the activity of caspase-3 in the cerebral cortex.

  7. Suppressive effect of FSH (show BRD2 ELISA Kits) and LH on p53 (show TP53 ELISA Kits) expression and caspase-3 activity with parallel increase in bcl-2 (show BCL2 ELISA Kits) expression and increased P production was observed

  8. Ischemic preconditioning exerts a powerful protective effect against hepatic ischemia-reperfusion injury in the early phase of reperfusion, which may be mediated by preservation of mitochondrial structure and inhibition of caspase-3 activity.

Rabbit Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 expression as well as low Bcl-2 (show BCL2 ELISA Kits) expression.

  2. This study revealed that the 810-nm low-level laser can improve cartilage structure, prevent articular cartilage degradation and significantly decrease the expression of caspase-3 in this surgery-induced osteoarthritis model.

  3. Morphine hypoxic preconditioning can protect rabbits against acute kidney hypoxic/reoxygenation injury by decreasing expression of caspase-3.

  4. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 (show BCL2 ELISA Kits) and down-regulating the activation of caspase-3.

  5. High frequency oscillatory ventilation combined with exogenous pulmonary surfactant can decrease the concentration of caspase-3 and p73 (show ARHGAP24 ELISA Kits) rabbit with acute respiratory failure.

Xenopus laevis Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) interaction partners

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3-dependent Proteolysis of JNK1 (show MAPK8 ELISA Kits)-2 and Bid (show BID ELISA Kits).

  2. in the developing diencephalon, Caspase3 acts downstream of Barhl2 (show BARHL2 ELISA Kits) in limiting neuroepithelial cell proliferation by inhibiting beta-catenin (show CTNNB1 ELISA Kits) activation.

  3. PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53 (show TP53 ELISA Kits)-dependent and p53 (show TP53 ELISA Kits)-independent apoptosis during development.

Caspase 3 (CASP3) Antigen Profile

Antigen Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Alternative names and synonyms associated with Caspase 3 (CASP3)

  • caspase 3, apoptosis-related cysteine peptidase (CASP3) Elisa Kit
  • death executioner caspase related to Apopain/Yama (decay) Elisa Kit
  • CG7788 gene product from transcript CG7788-RA (Ice) Elisa Kit
  • caspase 3 (Casp3) Elisa Kit
  • caspase 3, apoptosis-related cysteine peptidase (Casp3) Elisa Kit
  • caspase 3, apoptosis-related cysteine peptidase (casp3) Elisa Kit
  • A830040C14Rik Elisa Kit
  • AC-3 Elisa Kit
  • Apopain Elisa Kit
  • Cas3 Elisa Kit
  • Casp 3 Elisa Kit
  • Casp3 Elisa Kit
  • caspase-3 Elisa Kit
  • caspase 3 Elisa Kit
  • CC3 Elisa Kit
  • CG7788 Elisa Kit
  • CG14902 Elisa Kit
  • CPP32 Elisa Kit
  • CPP32B Elisa Kit
  • crice Elisa Kit
  • Decay Elisa Kit
  • Dmel\\CG7788 Elisa Kit
  • Dmel\\CG14902 Elisa Kit
  • drice Elisa Kit
  • Drosophila executioner caspase related to Apopain/Yama Elisa Kit
  • ice Elisa Kit
  • Lice Elisa Kit
  • mldy Elisa Kit
  • SCA-1 Elisa Kit
  • xcpp32 Elisa Kit
  • Yama Elisa Kit

Protein level used designations for CASP3

Caspase-3-like protein , caspase-3 , CG14902-PA , Caspase-3 , caspase 3 , caspase-3 protein , cleaved caspase 3 , decay-PA , CG7788-PA , Ice-PA , drice , interleukin-1beta-converting enzyme , CASP-3 , CPP-32 , SCA-1 , SREBP cleavage activity 1 , caspase 3, apoptosis related cysteine protease , cysteine protease CPP32 , protein Yama , CPP32beta , Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease) , Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease) , IRP , apopain , yama protein , PARP cleavage protease , caspase 3, apoptosis-related cysteine protease , procaspase3

GENE ID SPECIES
100034083 Equus caballus
42008 Drosophila melanogaster
43514 Drosophila melanogaster
12367 Mus musculus
25402 Rattus norvegicus
836 Homo sapiens
408016 Bos taurus
403567 Canis lupus familiaris
397244 Sus scrofa
443031 Ovis aries
100008840 Oryctolagus cuniculus
395476 Gallus gallus
100718309 Cavia porcellus
493932 Felis catus
397720 Xenopus laevis
461669 Pan troglodytes
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