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Caspase 3 Proteins

(Caspase 3 (CASP3))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].
Caspase 3 Protein (CASP3) (AA 29-277) (His-IF2DI Tag) Caspase 3 Protein (CASP3) (AA 29-277) (His-IF2DI Tag) Caspase 3 Protein (CASP3) (AA 29-277) (His-IF2DI Tag) (ABIN7122165)

CASP3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

Caspase 3 Protein (CASP3) (AA 176-277) (His tag) Caspase 3 Protein (CASP3) (AA 176-277) (His tag) Caspase 3 Protein (CASP3) (AA 176-277) (His tag) (ABIN3121034)

Crystallography grade CASP3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Caspase 3 Protein (CASP3) (AA 176-277) (His tag) Caspase 3 Protein (CASP3) (AA 176-277) (His tag) Caspase 3 Protein (CASP3) (AA 176-277) (His tag) (ABIN3090488)

Crystallography grade CASP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Caspase 3 Proteins by Grade

Find Caspase 3 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Caspase 3 Proteins by Origin

Find Caspase 3 Proteins for a variety of species such as anti-Human Caspase 3, anti-Mouse Caspase 3, anti-Rat Caspase 3. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 3 Proteins by Source

Here you will find Caspase 3 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Caspase 3 Proteins by Protein Type

Here you can find Caspase 3 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Caspase 3 Proteins by Application

Find Caspase 3 Proteins validated for a specific application such as ELISA, WB, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Caspase 3 Proteins by Biological Activity

Find Caspase 3 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Caspase 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122165
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3121034
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3090488
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3121035
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3090487
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505516
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424746
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391381
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411069
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391384
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415263
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400087
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5712415
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348103
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348105
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Caspase 3 Proteins

Qi, Sun, Tian, Xu, Zhang, Wang, Ma, Xu, Jin: "Fast Activation and Tracing of Caspase-3 Involved Cell Apoptosis by Combined Electrostimulation and Smart Signal-Amplified SERS Nanoprobes." in: Analytical chemistry, Vol. 92, Issue 11, pp. 7861-7868, (2020) (PubMed).

Mishra, Sharma, Sharma, Singh, Sardesai, Sharma, Mishra: "Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells." in: Journal of ethnopharmacology, Vol. 219, pp. 91-102, (2018) (PubMed).

Zhou, Li, Tian, Wang, Ding, Pang: "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis." in: Human & experimental toxicology, Vol. 33, Issue 7, pp. 761-71, (2015) (PubMed).

Pianu, Lefort, Thuiliere, Tabourier, Bartolini: "The Aβ₁₋₄₂ peptide regulates microtubule stability independently of tau." in: Journal of cell science, Vol. 127, Issue Pt 5, pp. 1117-27, (2014) (PubMed).

Xia, Yang, Bu, Ji, Zhao, Zheng, Lin, Li, Lu: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).

Nakajima, Hammond, Rosales, Shearer, Azuma: "Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 10, pp. 7059-67, (2011) (PubMed).

Chiou, Hodges, Hoa: "Suppression of growth arrest and DNA damage-inducible 45alpha expression confers resistance to sulindac and indomethacin-induced gastric mucosal injury." in: The Journal of pharmacology and experimental therapeutics, Vol. 334, Issue 3, pp. 693-702, (2010) (PubMed).

Choi, Feng, Yoon: "FKBP38 protects Bcl-2 from caspase-dependent degradation." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9770-9, (2010) (PubMed).

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Aliases for Caspase 3 Proteins

caspase 3 (CASP3) Proteins
caspase 3 (Casp3) Proteins
caspase 3 S homeolog (casp3.S) Proteins
caspase 3, apoptosis-related cysteine peptidase a (casp3a) Proteins
caspase 3, apoptosis-related cysteine peptidase (Casp3) Proteins
A830040C14Rik Proteins
AC-3 Proteins
Apopain Proteins
CASP-3 Proteins
casp3 Proteins
Caspase-3 Proteins
caspase-3 Proteins
CC3 Proteins
CPP32 Proteins
CPP32B Proteins
Lice Proteins
mldy Proteins
SCA-1 Proteins
xcpp32 Proteins
Yama Proteins
zgc:100890 Proteins
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