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Browse our anti-Caspase 4 (CASP4) Antibodies

Full name:
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase Antibodies (CASP4)
On www.antibodies-online.com are 234 Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies from 30 different suppliers available. Additionally we are shipping Caspase 4 Kits (73) and Caspase 4 Proteins (23) and many more products for this protein. A total of 344 Caspase 4 products are currently listed.
Synonyms:
CASP1, CASP4, Casp11, CASP13, Caspl, ICE(rel)II, ICEREL-II, ICH-2, ich-3, Mih1/TX, TX
list all antibodies Gene Name GeneID UniProt
CASP4 837 P49662
CASP4 12363 P70343
CASP4 114555  

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All available anti-Caspase 4 Antibodies

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Top referenced anti-Caspase 4 Antibodies

  1. Human Polyclonal Caspase 4 Primary Antibody for EIA, IHC (p) - ABIN499563 : Gracie, Robertson, McInnes: Interleukin-18. in Journal of leukocyte biology 2003 (PubMed)
    Show all 4 references for ABIN499563

  2. Human Polyclonal Caspase 4 Primary Antibody for IHC (p), WB - ABIN121890 : Cohen: Caspases: the executioners of apoptosis. in The Biochemical journal 1997 (PubMed)
    Show all 4 references for ABIN121890

  3. Human Polyclonal Caspase 4 Primary Antibody for EIA, IF - ABIN499561 : Kamens, Paskind, Hugunin, Talanian, Allen, Banach, Bump, Hackett, Johnston, Li: Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. in The Journal of biological chemistry 1995 (PubMed)
    Show all 4 references for ABIN499561

  4. Human Monoclonal Caspase 4 Primary Antibody for WB - ABIN967534 : Faucheu, Diu, Chan, Blanchet, Miossec, Hervé, Collard-Dutilleul, Gu, Aldape, Lippke: A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. in The EMBO journal 1995 (PubMed)
    Show all 2 references for ABIN967534

  5. Human Polyclonal Caspase 4 Primary Antibody for WB - ABIN374466 : Munday, Vaillancourt, Ali, Casano, Miller, Molineaux, Yamin, Yu, Nicholson: Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. in The Journal of biological chemistry 1995 (PubMed)

  6. Mouse (Murine) Polyclonal Caspase 4 Primary Antibody for WB - ABIN222879 : Huang, Xie, Qiao, Qiu, Huang, Li, Chen, Liu, Wang, Lin, Wang: Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. in Toxicological sciences : an official journal of the Society of Toxicology 2015 (PubMed)

  7. Human Polyclonal Caspase 4 Primary Antibody for WB - ABIN222883 : Kim, Zhang, Hitomi, Lee, Mukherjee: Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. in Human molecular genetics 2006 (PubMed)

More Antibodies against Caspase 4 Interaction Partners

Human Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Caspase-4 and caspase-5 (show CASP5 Antibodies) mediate IL-1alpha and IL-1beta (show IL1B Antibodies) release from human monocytes after lipopolysaccharides stimulation.

  2. both caspase-4 and caspase-5 (show CASP5 Antibodies) are functionally important for appropriate responses to intracellular Gram-negative bacteria.

  3. caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 (show NLRP3 Antibodies) inflammasome activation to drive IL-1beta (show IL1B Antibodies) maturation.

  4. This study reveled that CASP4 having a central role in the bipolar disease and schizophrenia manifestation.

  5. NF-kappaB (show NFKB1 Antibodies) can mediate Fas (show FAS Antibodies)-induced apoptosis through caspase-4 protease

  6. implicate caspase-4 as a critical regulator of noncanonical inflammasome activation that initiates defense against bacterial pathogens in primary macrophages

  7. Authors observed increases in the endoplasmic reticulum stress markers BiP (show GDF10 Antibodies) and cleaved caspase-4 in Duchenne muscular dystrophy (show DMD Antibodies) patient biopsies, compared with controls.

  8. The caspase-4/11 inflammasome also governs activation of the proinflammatory cytokine, interleukin (IL)-18 (show IL18 Antibodies), in response to intracellular and extracellular enteric pathogens.

  9. function of caspase-4/5/11 represents a new mode of pattern recognition in immunity and also an unprecedented means of caspase (show CASP3 Antibodies) activation

  10. caspase-4 can support activation of caspase-1 (show CASP1 Antibodies) and secretion of IL-1beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies) in response to priming signals (LPS (show IRF6 Antibodies) or Pam3CSK4) alon

Mouse (Murine) Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Hyperactive dendritic cells induce potent adaptive immune responses and are elicited by caspase-11, an enzyme that binds oxidized phospholipids and bacterial lipopolysaccharide.

  2. Caspase-1 (show CASP1 Antibodies)-activated IL-18 (show IL18 Antibodies) induces IFN-gamma (show IFNG Antibodies) to prime caspase-11 and rapidly clear Burkholderia thailandensis infection.

  3. These results argue that caspase-1 (show CASP1 Antibodies), -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  4. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  5. But not in Casp11(-/-), Panx1 (show PANX1 Antibodies)(-/-), or P2x7 (show P2RX7 Antibodies)(-/-) mice.

  6. active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3 (show NLRP3 Antibodies).

  7. Data show that caspase-1 (show CASP1 Antibodies) but not caspase-11 was essential for the functional activities of the NLRC4 (show NLRC4 Antibodies) inflammasome.

  8. Data indicate that genetic ablation of caspase-1 (show CASP1 Antibodies) and -11 from cpdm (show SHARPIN Antibodies) mice significantly reduced skin inflammation in sharpin (show SHARPIN Antibodies)-deficient mice.

  9. These results suggest a role for other caspase-11 effector mechanisms such as pyroptosis in protection against intestinal inflammation.

  10. Caspase-11 limits the response of CD8 (show CD8A Antibodies)+ T-cells to low-abundance and low-affinity antigens.

Caspase 4 (CASP4) Antigen Profile

Antigen Summary

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 4 (CASP4)

  • caspase 4 (CASP4) antibody
  • caspase 11 (LOC100101589) antibody
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) antibody
  • caspase 4, apoptosis-related cysteine peptidase (Casp4) antibody
  • caspase-4-like (LOC100359184) antibody
  • CASP1 antibody
  • CASP4 antibody
  • Casp11 antibody
  • CASP13 antibody
  • Caspl antibody
  • ICE(rel)II antibody
  • ICEREL-II antibody
  • ICH-2 antibody
  • ich-3 antibody
  • Mih1/TX antibody
  • TX antibody

Protein level used designations for CASP4

caspase 4 , CASP-4 , ICE(rel)-II , apoptotic cysteine protease Mih1/TX , caspase 4, apoptosis-related cysteine protease , caspase-4 , protease ICH-2 , protease TX , CASP-11 , caspase 11, apoptosis-related cysteine peptidase , caspase 11, apoptosis-related cysteine protease , caspase-11 short form splicing , protease ICH-3 , caspase 11 , CASP-1 , ICE , IL-1 beta-converting enzyme , IL-1BC , caspase-1 , caspase-1/caspase-4 hybrid , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , CASP-13 , ERICE , caspase 13 , caspase-13 , evolutionary related interleukin-1-beta-converting enzyme

GENE ID SPECIES
704864 Macaca mulatta
100101589 Oryctolagus cuniculus
837 Homo sapiens
12363 Mus musculus
114555 Rattus norvegicus
403724 Canis lupus familiaris
338039 Bos taurus
100359184 Oryctolagus cuniculus
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