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anti-Human Caspase 4 antibody for Western Blotting

Recommended Caspase 4 Antibody (supplied by: Log in to see )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
  • CASP4
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • Caspl
  • ich-3
  • CASP1
  • CASP13
  • caspase 4
  • caspase 11
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4-like
  • CASP4
  • LOC100101589
  • Casp4
  • LOC100359184
Reactivity
Human, Mouse (Murine), Rat (Rattus)
180
108
45
19
3
1
1
Host
Rabbit
185
30
21
16
6
Clonality
Polyclonal
Conjugate
This Caspase 4 antibody is un-conjugated
15
13
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
233
109
73
58
32
27
23
19
13
9
8
6
3
2
1
1
Options
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Catalog No. ABIN222883
$ 283.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0923712 ABIN499561 EIA IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 4
3.0923712 ABIN265762 ELISA ICC IF IHC IHC (fro) IHC (p) IP MA WB Rat IgG2a Log in to see 17D9 21
3.0923712 ABIN499563 EIA IHC (p) WB Rabbit IgG Intermediate Domain Log in to see Polyclonal 4
3.0923712 ABIN967534 WB Mouse IgG1, kappa Log in to see B25-1 2
3.0923712 ABIN268673 ELISA WB Goat Log in to see Polyclonal 1
3.0923712 ABIN2787904 WB Rabbit Middle Region Log in to see Polyclonal
3.0923712 ABIN155063 WB Mouse IgG1 N-Term Log in to see D44
3.0923712 ABIN1536104 ELISA WB Rabbit IgG Cleaved-Gln81 Log in to see Polyclonal
3.0923712 ABIN2787905 WB Rabbit Middle Region Log in to see Polyclonal
3.0923712 ABIN3043186 IHC (p) WB Rabbit IgG AA 104-124, N-Term Log in to see Polyclonal
3.0923712 ABIN615322 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
3.0923712 ABIN2705686 IHC WB Rabbit Center Log in to see Polyclonal
3.0923712 ABIN498677 IHC (p) WB Rabbit Log in to see Polyclonal
3.0923712 ABIN2465498 ELISA WB Goat Internal Region Log in to see Polyclonal
3.0923712 ABIN4288124 WB Rabbit IgG1 N-Term Log in to see D44
3.0923712 ABIN4288129 WB Mouse IgG1 Log in to see 4A2
3.0923712 ABIN615323 IHC (p) WB Rabbit Log in to see Polyclonal
3.0923712 ABIN4288127 ELISA ICC IF IHC IHC (p) WB Rabbit Center Log in to see Polyclonal
3.0923712 ABIN4288126 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
3.0923712 ABIN1858247 ICC IHC IP WB Rabbit IgG AA 290-377 Log in to see Polyclonal

Top referenced anti-Caspase 4 antibody for Western Blotting

Similar anti-Caspase 4 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 3 Antibodies
Western Blotting (WB) 170 Antibodies 93 Antibodies 34 Antibodies
Microarray (MA) 5 Antibodies 4 Antibodies
Immunoprecipitation (IP) 13 Antibodies 5 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 54 Antibodies 36 Antibodies 7 Antibodies
Immunohistochemistry (IHC) 55 Antibodies 26 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 20 Antibodies 1 Antibodies

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(180), (108), (45), (19), (3), (1), (1)
Host Rabbit
(185), (30), (21), (16), (6)
Clonality
Polyclonal
Conjugate This Caspase 4 antibody is un-conjugated
(15), (13), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(233), (109), (73), (58), (32), (27), (23), (19), (13), (9), (8), (6), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Caspase 4 Antibody

Target Details Caspase 4 Application Details Handling References for anti-Caspase 4 Antibody (ABIN222883) Images
Blocking Peptide Blocking peptide for this product available: ABIN412652
Specificity The affinity purified antibody detects the 43 kDa proform of caspase-4.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 100 of human caspase-4
Isotype IgG

Target Details Caspase 4

Product Details anti-Caspase 4 Antibody Application Details Handling References for anti-Caspase 4 Antibody (ABIN222883) Images back to top
Antigen
Alternative Name Caspase-4 (CASP4 Antibody Abstract)
Background Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-4 is also known as Ich-2, TX, and ICErel-II and can proteolytically processed by granzyme B. Over expression of caspase-4 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.
Synonyms: CASP-4, ICH-2 protease, TX protease, ICH2
Gene ID 837
UniProt P49662
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling References for anti-Caspase 4 Antibody (ABIN222883) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL). However, the optimal conditions should be determined individually. The affinity purified antibody detects the 43 kDa proform of caspase-4.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details References for anti-Caspase 4 Antibody (ABIN222883) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 4 Antibody (ABIN222883)

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling Images back to top
Product cited in:

Kim, Zhang, Hitomi, Lee, Mukherjee: "Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL." in: Human molecular genetics, Vol. 15, Issue 11, pp. 1826-34, 2006

Images

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling References for anti-Caspase 4 Antibody (ABIN222883) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN222883) Western blot analysis of caspase-4 expression in HeLa cell extract. Caspase-4