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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Immunocytochemistry (ICC)||8 Antibodies|
|Immunofluorescence (IF)||10 Antibodies|
|Immunofluorescence (Cultured Cells) (IF (cc))||1 Antibodies|
|Immunohistochemistry (IHC)||51 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||3 Antibodies|
|Immunohistochemistry (Formalin-fixed Sections) (IHC (f))||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||4 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||38 Antibodies|
|Western Blotting (WB)||153 Antibodies|
|Antigen||Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies|
|Conjugate||This Caspase 4 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-Caspase 4 AntibodyTarget Details Caspase 4 Application Details Handling References for anti-Caspase 4 Antibody (ABIN223055) Images
|Specificity||Detects the 43 kDa human caspase-4 .|
|Immunogen||Synthetic peptide corresponding to the N-terminus of human Caspase-4|
Target Details Caspase 4Product Details anti-Caspase 4 Antibody Application Details Handling References for anti-Caspase 4 Antibody (ABIN223055) Images back to top
|Alternative Name||Caspase-4 (CASP4 Antibody Abstract)|
The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family, caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis.
Synonyms: CASP-4, ICH-2 protease, TX protease, ICH2
|Pathways||Apoptosis, Caspase Cascade in Apoptosis|
Application DetailsProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling References for anti-Caspase 4 Antibody (ABIN223055) Images back to top
Western blotting (0.5-4 μg/mL).
293 cell lysate can be used as a positive control.
However, the optimal conditions should be determined individually.
Country of Animal Origin: USA
|Restrictions||For Research Use only|
HandlingProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details References for anti-Caspase 4 Antibody (ABIN223055) Images back to top
|Buffer||100 μg (0.5 mg/mL) immunoaffinity purified mouse IgG in PBS containing 0.5 % BSA, 1.5 mM sodium azide and 30 % glycerol.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
|Storage Comment||For long-term storage, aliquot and freeze at -70 °C.|
|Expiry Date||12 months|
References for anti-Caspase 4 Antibody (ABIN223055)Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling Images back to top
|Product cited in:||
Kim, Zhang, Hitomi, Lee, Mukherjee: "Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL." in: Human molecular genetics, Vol. 15, Issue 11, pp. 1826-34, 2006
ImagesProduct Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling References for anti-Caspase 4 Antibody (ABIN223055) back to top