anti-Mouse (Murine) Caspase 4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 4 Antibody (supplied by: Log in to see )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
  • CASP4
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • Caspl
  • ich-3
  • CASP1
  • CASP13
  • caspase 4
  • caspase 11
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4-like
  • CASP4
  • LOC100101589
  • Casp4
  • LOC100359184
Reactivity
Human, Mouse (Murine)
183
108
47
19
3
1
1
Host
Rat
189
29
21
16
7
Clonality
Monoclonal
Conjugate
This Caspase 4 antibody is un-conjugated
15
13
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
237
109
72
59
31
26
22
18
13
9
8
5
3
2
1
1
Supplier
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Catalog No. ABIN265762
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.400779 ABIN498677 IHC (p) WB Rabbit Log in to see Polyclonal
13.400779 ABIN872827 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
13.400779 ABIN4288127 ELISA ICC IF IHC IHC (p) WB Rabbit Center Log in to see Polyclonal
13.400779 ABIN4288126 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
13.400779 ABIN4288125 IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN121890 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 4
1 ABIN5554659 EIA IF IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2477914 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 3
1 ABIN303366 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN462473 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN320487 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN214595 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1732653 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN886623 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN4288034 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Rat IgG2a Log in to see 17D9
1 ABIN4288037 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 700 Rat IgG2a Log in to see 17D9
1 ABIN4288040 ELISA ICC IF IHC (fro) IHC (p) WB DyLight 350 Rat IgG2a Log in to see 17D9
1 ABIN4288043 ELISA ICC IF IHC (fro) IHC (p) WB DyLight 488 Rat IgG2a Log in to see 17D9
1 ABIN4288035 ELISA ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rat IgG2a Log in to see 17D9
1 ABIN4288044 ELISA ICC IF IHC (fro) IHC (p) WB DyLight 550 Rat IgG2a Log in to see 17D9

Top referenced anti-Caspase 4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Caspase 4 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 46 Antibodies 72 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 8 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 24 Antibodies 24 Antibodies
Immunofluorescence (IF) 21 Antibodies 25 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 26 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 20 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies
Immunoprecipitation (IP) 13 Antibodies
Microarray (MA) 5 Antibodies
Western Blotting (WB) 93 Antibodies

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
Reactivity Human, Mouse (Murine)
(183), (108), (47), (19), (3), (1), (1)
Host Rat
(189), (29), (21), (16), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 4 antibody is un-conjugated
(15), (13), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
(237), (109), (72), (59), (31), (26), (22), (18), (13), (9), (8), (5), (3), (2), (1), (1)
Pubmed 20 references available
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Product Details anti-Caspase 4 Antibody

Target Details Caspase 4 Application Details Handling ProductDetails: References for anti-Caspase 4 antibody (ABIN265762) Images
Purification Protein G purified
Immunogen A recombinant p30 subunit of mouse Caspase 11. [UniProt# P70343]
Clone 17D9
Isotype IgG2a

Target Details Caspase 4

Product Details anti-Caspase 4 Antibody Application Details Handling ProductDetails: References for anti-Caspase 4 antibody (ABIN265762) Images back to top
Antigen
Alternative Name Caspase-11 (CASP4 Antibody Abstract)
Background Gene Symbol: CASP11
Molecular Weight Theoretical MW: 35-43 kDa
Gene ID 12363
UniProt P70343
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling ProductDetails: References for anti-Caspase 4 antibody (ABIN265762) Images back to top
Application Notes Western Blot 5 μg/mL, ELISA, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:100, Immunoprecipitation, Immunohistochemistry-Paraffin 1:100, Immunohistochemistry-Frozen 1:10-1:500, MicroarrayUse in immunprecipitation reported in scientific literature (PMID 10791975) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details ProductDetails: References for anti-Caspase 4 antibody (ABIN265762) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ProductDetails: References for anti-Caspase 4 antibody (ABIN265762)

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling Images back to top
Product cited in:

Man, Karki, Briard, Burton, Gingras, Pelletier, Kanneganti: "Differential roles of caspase-1 and caspase-11 in infection and inflammation." in: Scientific reports, Vol. 7, pp. 45126, 2017 (Sample species: Mouse (Murine)).

Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Chung, Vilaysane, Lau, Stahl, Morampudi, Bondzi-Simpson, Platnich, Bracey, French, Beck, Chun, Vallance, Muruve: "NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis." in: Cell death and differentiation, Vol. 23, Issue 8, pp. 1331-46, 2016 (Sample species: Mouse (Murine)). Further details: Western Blotting

Kim, Bae, Ryu, Kwon, Oh, Kwon, Moon, Kim, Miyawaki, Lee, Shin, Kim, Kim, Ryter, Choi, Rhee, Ryu, Yoon: "SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages." in: Autophagy, Vol. 12, Issue 8, pp. 1272-91, 2016 Further details: Western Blotting,Immunoprecipitation

Klaska, Muckersie, Martin-Granados, Christofi, Forrester: "Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms." in: Immunology, Vol. 150, Issue 3, pp. 364-377, 2016

Youm, Nguyen, Grant, Goldberg, Bodogai, Kim, DAgostino, Planavsky, Lupfer, Kanneganti, Kang, Horvath, Fahmy, Crawford, Biragyn, Alnemri, Dixit: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." in: Nature medicine, Vol. 21, Issue 3, pp. 263-9, 2015 (Sample species: Human). Further details: Western Blotting

Aachoui, Kajiwara, Leaf, Mao, Ting, Coers, Aderem, Buxbaum, Miao: "Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium." in: Cell host & microbe, Vol. 18, Issue 3, pp. 320-32, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting

Shi, Zhao, Wang, Shi, Wang, Huang, Zhuang, Cai, Wang, Shao: "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death." in: Nature, Vol. 526, Issue 7575, pp. 660-5, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting

Kayagaki, Stowe, Lee, ORourke, Anderson, Warming, Cuellar, Haley, Roose-Girma, Phung, Liu, Lill, Li, Wu, Kummerfeld, Zhang, Lee, Snipas, Salvesen, Morris, Fitzgerald, Zhang, Bertram, Goodnow, Dixit: "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling." in: Nature, Vol. 526, Issue 7575, pp. 666-71, 2015 (Sample species: Mouse (Murine)). Further details: Western Blotting

Diabate, Munro, Garcia, Jacquel, Michel, Obba, Goncalves, Luci, Marchetti, Demon, Degos, Bechah, Mege, Lamkanfi, Auberger, Gorvel, Stuart, Landraud, Lemichez, Boyer: "Escherichia coli ?-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004732, 2015 (Sample species: Mouse (Murine)). Further details: ELISA

Bonora, Wieckowsk, Chinopoulos, Kepp, Kroemer, Galluzzi, Pinton: "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition." in: Oncogene, Vol. 34, Issue 12, pp. 1608, 2015

Yuan, Syed, Panchal, Joo, Colonna, Brantly, Sadikot: "Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival." in: The Journal of biological chemistry, Vol. 289, Issue 21, pp. 15118-29, 2014 (Sample species: Mouse (Murine)). Further details: Western Blotting

Gurung, Anand, Malireddi, Vande Walle, Van Opdenbosch, Dillon, Weinlich, Green, Lamkanfi, Kanneganti: "FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1835-46, 2014 (Sample species: Mouse (Murine)). Further details: Western Blotting

Van Opdenbosch, Gurung, Vande Walle, Fossoul, Kanneganti, Lamkanfi: "Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation." in: Nature communications, Vol. 5, pp. 3209, 2014 Further details: Western Blotting

Case, Kohler, Lima, Strowig, de Zoete, Flavell, Zamboni, Roy: "Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1851-6, 2013 (Sample species: Mouse (Murine)). Further details: Western Blotting

Jin, Oda, Lai, Skalsky, Bethel, Shepherd, Kang, Liu, Sabouri-Ghomi, Cullen, Rajewsky, Xiao: "MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways." in: The EMBO journal, Vol. 32, Issue 17, pp. 2377-91, 2013 (Sample species: Mouse (Murine)). Further details: Western Blotting

Kenneth, Younger, Hughes, Marcotte, Barker, Saunders, Duckett: "An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1." in: The Biochemical journal, Vol. 443, Issue 2, pp. 355-9, 2012 (Sample species: Mouse (Murine)). Further details: Western Blotting

Sun, Wu, Hayashi, Peters, Tsuda, Inoue, Nakanishi: "Microglial cathepsin B contributes to the initiation of peripheral inflammation-induced chronic pain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 33, pp. 11330-42, 2012 (Sample species: Mouse (Murine)). Further details: Western Blotting

Kayagaki, Warming, Lamkanfi, Vande Walle, Louie, Dong, Newton, Qu, Liu, Heldens, Zhang, Lee, Roose-Girma, Dixit: "Non-canonical inflammasome activation targets caspase-11." in: Nature, Vol. 479, Issue 7371, pp. 117-21, 2011

Kang, Wang, Kuida, Yuan: "Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response." in: Cell death and differentiation, Vol. 9, Issue 10, pp. 1115-25, 2002 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Images

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling ProductDetails: References for anti-Caspase 4 antibody (ABIN265762) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Immunohistochemistry-Paraffin: Caspase 11 Antibody (17D9) [ABIN2657624] - IHC-P analy...
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse B cell. Image from ver...
Immunofluorescence (IF) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Immunocytochemistry/Immunofluorescence: Caspase 11 Antibody (17D9) [ABIN2657624] - Ca...
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - Mouse liver extract was sepa...
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Western Blot: Caspase 11 Antibody (17D9) [ABIN2657624] - analysis of Caspase 11 in LP...
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN265762) Western Blot: Caspase-11 Antibody (17D9) [ABIN2657624] - Analysis of Caspase-11 in TH...