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Browse our Caspase 4 (CASP4) ELISA Kits

Full name:
Caspase 4, Apoptosis-Related Cysteine Peptidase ELISA Kits (CASP4)
On are 73 Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) ELISA Kits from 8 different suppliers available. Additionally we are shipping Caspase 4 Antibodies (234) and Caspase 4 Proteins (23) and many more products for this protein. A total of 344 Caspase 4 products are currently listed.
CASP1, CASP4, Casp11, CASP13, Caspl, ICE(rel)II, ICEREL-II, ICH-2, ich-3, Mih1/TX, TX
list all ELISA KIts Gene Name GeneID UniProt
CASP4 837 P49662
CASP4 12363 P70343
CASP4 114555  

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More ELISA Kits for Caspase 4 Interaction Partners

Human Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. apoptosis is induced by rhein traditional Chinese medicine via induction of endoplasmic reticulum stress, caspase-4 and intracellular calcium in primary human hepatic HL-7702 cells

  2. Caspase-4 and caspase-5 (show CASP5 ELISA Kits) mediate IL-1alpha and IL-1beta (show IL1B ELISA Kits) release from human monocytes after lipopolysaccharides stimulation.

  3. both caspase-4 and caspase-5 (show CASP5 ELISA Kits) are functionally important for appropriate responses to intracellular Gram-negative bacteria.

  4. caspase-4 activation alone is sufficient to induce pyroptosis, this process depends on the NLRP3 (show NLRP3 ELISA Kits) inflammasome activation to drive IL-1beta (show IL1B ELISA Kits) maturation.

  5. This study reveled that CASP4 having a central role in the bipolar disease and schizophrenia manifestation.

  6. NF-kappaB (show NFKB1 ELISA Kits) can mediate Fas (show FAS ELISA Kits)-induced apoptosis through caspase-4 protease

  7. implicate caspase-4 as a critical regulator of noncanonical inflammasome activation that initiates defense against bacterial pathogens in primary macrophages

  8. Authors observed increases in the endoplasmic reticulum stress markers BiP (show GDF10 ELISA Kits) and cleaved caspase-4 in Duchenne muscular dystrophy (show DMD ELISA Kits) patient biopsies, compared with controls.

  9. The caspase-4/11 inflammasome also governs activation of the proinflammatory cytokine, interleukin (IL)-18 (show IL18 ELISA Kits), in response to intracellular and extracellular enteric pathogens.

  10. function of caspase-4/5/11 represents a new mode of pattern recognition in immunity and also an unprecedented means of caspase (show CASP3 ELISA Kits) activation

Mouse (Murine) Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) interaction partners

  1. Hyperactive dendritic cells induce potent adaptive immune responses and are elicited by caspase-11, an enzyme that binds oxidized phospholipids and bacterial lipopolysaccharide.

  2. Caspase-1 (show CASP1 ELISA Kits)-activated IL-18 (show IL18 ELISA Kits) induces IFN-gamma (show IFNG ELISA Kits) to prime caspase-11 and rapidly clear Burkholderia thailandensis infection.

  3. These results argue that caspase-1 (show CASP1 ELISA Kits), -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  4. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  5. But not in Casp11(-/-), Panx1 (show PANX1 ELISA Kits)(-/-), or P2x7 (show P2RX7 ELISA Kits)(-/-) mice.

  6. active caspase-11 leads to a drop of intracellular potassium levels, which is necessary to activate NLRP3 (show NLRP3 ELISA Kits).

  7. Data show that caspase-1 (show CASP1 ELISA Kits) but not caspase-11 was essential for the functional activities of the NLRC4 (show NLRC4 ELISA Kits) inflammasome.

  8. Data indicate that genetic ablation of caspase-1 (show CASP1 ELISA Kits) and -11 from cpdm (show SHARPIN ELISA Kits) mice significantly reduced skin inflammation in sharpin (show SHARPIN ELISA Kits)-deficient mice.

  9. These results suggest a role for other caspase-11 effector mechanisms such as pyroptosis in protection against intestinal inflammation.

  10. Caspase-11 limits the response of CD8 (show CD8A ELISA Kits)+ T-cells to low-abundance and low-affinity antigens.

Caspase 4 (CASP4) Antigen Profile

Antigen Summary

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 4 (CASP4)

  • caspase 4 (CASP4) Elisa Kit
  • caspase 11 (LOC100101589) Elisa Kit
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) Elisa Kit
  • caspase 4, apoptosis-related cysteine peptidase (Casp4) Elisa Kit
  • caspase-4-like (LOC100359184) Elisa Kit
  • CASP1 Elisa Kit
  • CASP4 Elisa Kit
  • Casp11 Elisa Kit
  • CASP13 Elisa Kit
  • Caspl Elisa Kit
  • ICE(rel)II Elisa Kit
  • ICEREL-II Elisa Kit
  • ICH-2 Elisa Kit
  • ich-3 Elisa Kit
  • Mih1/TX Elisa Kit
  • TX Elisa Kit

Protein level used designations for CASP4

caspase 4 , CASP-4 , ICE(rel)-II , apoptotic cysteine protease Mih1/TX , caspase 4, apoptosis-related cysteine protease , caspase-4 , protease ICH-2 , protease TX , CASP-11 , caspase 11, apoptosis-related cysteine peptidase , caspase 11, apoptosis-related cysteine protease , caspase-11 short form splicing , protease ICH-3 , caspase 11 , CASP-1 , ICE , IL-1 beta-converting enzyme , IL-1BC , caspase-1 , caspase-1/caspase-4 hybrid , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , CASP-13 , ERICE , caspase 13 , caspase-13 , evolutionary related interleukin-1-beta-converting enzyme

704864 Macaca mulatta
100101589 Oryctolagus cuniculus
837 Homo sapiens
12363 Mus musculus
114555 Rattus norvegicus
403724 Canis lupus familiaris
338039 Bos taurus
100359184 Oryctolagus cuniculus
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