anti-Mouse (Murine) Caspase 6 antibody for Western Blotting

Recommended Caspase 6 Antibody (supplied by: Log in to see )

Antigen
Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antibodies
  • xCaspase-6
  • mch2
  • caspase-6
  • zgc:112960
  • CASP6
  • casp6
  • Mch2
  • mCASP-6
  • MCH2
  • caspase 6, apoptosis-related cysteine peptidase
  • caspase 6
  • caspase-6
  • Caspase-6
  • caspase-6-like
  • casp6
  • CASP6
  • CpipJ_CPIJ017008
  • Casp6
  • LOC100341546
  • LOC100517293
Epitope
C-Term, Large Subunit
49
48
39
15
15
15
14
12
6
5
5
5
5
5
5
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
287
116
105
16
5
5
5
3
3
1
Host
Rabbit
276
21
19
Clonality
Polyclonal
Conjugate
This Caspase 6 antibody is un-conjugated
18
17
13
10
10
10
3
3
3
3
3
3
3
3
3
3
3
Application
Immunohistochemistry (IHC), Western Blotting (WB)
269
145
114
66
40
32
26
19
8
5
5
5
1
1
Options
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Catalog No. ABIN223017
$ 245.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9058776 ABIN2774243 WB Rabbit Middle Region Log in to see Polyclonal
2.9058776 ABIN2704577 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal
2.9058776 ABIN388106 IHC (p) WB Rabbit Ig AA 235-263, C-Term Log in to see Polyclonal 3
2.9058776 ABIN252116 ICC IHC (fro) IF IHC (p) IP IHC WB Rabbit Log in to see Polyclonal 4
2.9058776 ABIN1536083 IHC ELISA WB Rabbit IgG Cleaved-Asp162 Log in to see Polyclonal
2.9058776 ABIN1531214 IF IHC ELISA WB Rabbit IgG pSer257 Log in to see Polyclonal
2.9058776 ABIN3181943 ELISA IF IHC WB Rabbit IgG pSer257 Log in to see Polyclonal
2.9058776 ABIN3183669 ELISA IF IHC WB Rabbit IgG Ser1981 Log in to see Polyclonal
2.9058776 ABIN1532232 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN2862603 IF IHC ELISA WB Rabbit IgG pSer257 Log in to see Polyclonal
2.9058776 ABIN1871468 IHC WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN407883 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN3030311 IHC ELISA WB Rabbit Ig Fraction AA 235-263 Log in to see Polyclonal
2.9058776 ABIN3022545 IHC WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN3030314 IHC (fro) IHC (p) WB Rabbit IgG AA 7-27 Log in to see Polyclonal
2.9058776 ABIN2420999 ELISA WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN2427575 ELISA WB Rabbit IgG Log in to see Polyclonal
2.9058776 ABIN1853454 IHC ELISA WB Rabbit Internal Region, Asp162 Log in to see Polyclonal
1 ABIN222958 WB Rabbit IgG C-Term, Large Subunit, active Log in to see Polyclonal 1
1 ABIN5552008 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal

General

Antigen Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antibodies
Epitope C-Term, Large Subunit
(49), (48), (39), (15), (15), (15), (14), (12), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(287), (116), (105), (16), (5), (5), (5), (3), (3), (1)
Host Rabbit
(276), (21), (19)
Clonality
Polyclonal
Conjugate This Caspase 6 antibody is un-conjugated
(18), (17), (13), (10), (10), (10), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(269), (145), (114), (66), (40), (32), (26), (19), (8), (5), (5), (5), (1), (1)
Pubmed 2 references available
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Product Details anti-Caspase 6 Antibody

Target Details Caspase 6 Application Details Handling References for anti-Caspase 6 antibody (ABIN223017) Images
Blocking Peptide Blocking peptide for this product available: ABIN412654
Specificity The antibody detects a full length (35 kDa) and the cleaved fragment (18 kDa) of caspase-6.
Purification Affinity purified
Immunogen Synthetic peptide mapping to the C-terminus of rat caspase-6 large fragment
Isotype IgG

Target Details Caspase 6

Product Details anti-Caspase 6 Antibody Application Details Handling References for anti-Caspase 6 antibody (ABIN223017) Images back to top
Antigen
Alternative Name Caspase-6 (CASP6 Antibody Abstract)
Background Caspase-6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.
Synonyms: CASP6, CASP-6 , MCH2
Gene ID 83584
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Handling References for anti-Caspase 6 antibody (ABIN223017) Images back to top
Application Notes Western blotting (0.5-4 μg/mL), and Immunohistochemistry (5 μg/mL). However, the optimal conditions should be determined individually. Jurkat cell lysate, mouse intestine, and rat kidney tissue lysate can be used as a positive controls. The antibody detects a full length (35 kDa) and the cleaved fragment (18 kDa) of caspase-6.
Comment

Suggested positive control:
Western Blot:Rat kidney tissue lysate, full length and cleaved. IHC: Tonsil tissue

Restrictions For Research Use only

Handling

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details References for anti-Caspase 6 antibody (ABIN223017) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) rabbit anti-caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 6 antibody (ABIN223017)

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details Handling Images back to top
Product cited in:

Vohra, Sasaki, Miller, Chang, DiAntonio, Milbrandt: "Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13729-38, 2010

Nikolaev, McLaughlin, OLeary, Tessier-Lavigne: "APP binds DR6 to trigger axon pruning and neuron death via distinct caspases." in: Nature, Vol. 457, Issue 7232, pp. 981-9, 2009

Images

Product Details anti-Caspase 6 Antibody Target Details Caspase 6 Application Details Handling References for anti-Caspase 6 antibody (ABIN223017) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (C-Term), (Large Subunit) antibody (ABIN223017) Western blot analysis of Caspase-6 expression rat kidney tissue lysate. Both full len...