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anti-Human Caspase 7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 7 Antibody (supplied by: Log in to see )

Antigen
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) Antibodies
  • xCaspase-7
  • caspase-7
  • caspase7
  • cmh-1
  • ice-lap3
  • mch3
  • CASP7
  • AI314680
  • CMH-1
  • ICE-IAP3
  • Mch3
  • mCASP-7
  • CASP-7
  • ICE-LAP3
  • LICE2
  • MCH3
  • Caspase-7
  • MCH3/SCA-2
  • SCA-2
  • caspase-7-like
  • caspase-7
  • caspase 7, apoptosis-related cysteine peptidase
  • caspase 7
  • LOC100068258
  • xCaspase-7
  • casp7
  • CASP7
  • Casp7
  • LOC100156777
  • LOC100101591
Epitope
N-Term
30
28
12
7
7
6
6
6
6
6
5
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
292
115
93
8
7
5
5
4
4
2
2
1
Host
Rabbit
206
96
3
Clonality
Polyclonal
Conjugate
This Caspase 7 antibody is un-conjugated
14
12
9
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
250
105
96
69
37
19
15
14
8
5
4
3
2
1
1
1
Supplier
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Catalog No. ABIN783546
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.096846 ABIN783821 EIA IHC (p) WB Rabbit C-Term Log in to see Polyclonal 1
12.096846 ABIN252490 IHC (p) WB Mouse IgG1 Log in to see 25B881-1 1
12.096846 ABIN4288140 ELISA IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 1
12.096846 ABIN615325 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
12.096846 ABIN498546 IHC (p) WB Rabbit Log in to see Polyclonal
12.096846 ABIN4288142 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
12.096846 ABIN462356 IHC (p) WB Mouse IgG Log in to see 7-1-11
12.096846 ABIN462357 IHC (p) WB Mouse IgG Log in to see 10-1-62
1 ABIN127027 IHC (p) IP WB Rabbit active Log in to see Polyclonal
1 ABIN400716 IHC (p) WB Mouse IgG1 active Log in to see 25B881-1
1 ABIN614356 IHC (p) WB Mouse IgG Log in to see 07-01-11
1 ABIN4288137 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 2
1 ABIN3043217 IHC (p) WB Rabbit IgG AA 237-255, Middle Region Log in to see Polyclonal
1 ABIN3042355 IHC (p) WB Rabbit IgG AA 117-198 Log in to see Polyclonal
1 ABIN614357 IHC (p) WB Mouse IgG Log in to see 10-01-62
1 ABIN2891158 IHC (p) ELISA WB Rabbit IgG AA 180-229 Log in to see Polyclonal
1 ABIN2891157 IHC (p) ELISA WB Rabbit IgG AA 149-198 Log in to see Polyclonal
1 ABIN121893 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 3
1 ABIN298976 IHC (p) WB Mouse IgG1 Log in to see 25B881-1
1 ABIN462478 IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Top referenced anti-Caspase 7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Caspase 7 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 11 Antibodies 30 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 5 Antibodies
Immunofluorescence (IF) 3 Antibodies 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 32 Antibodies 46 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 45 Antibodies
Immunoprecipitation (IP) 12 Antibodies
Simple Western (SimWes) 1 Antibodies
Western Blotting (WB) 75 Antibodies

General

Antigen Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) Antibodies
Epitope N-Term
(30), (28), (12), (7), (7), (6), (6), (6), (6), (6), (5), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(292), (115), (93), (8), (7), (5), (5), (4), (4), (2), (2), (1)
Host Rabbit
(206), (96), (3)
Clonality
Polyclonal
Conjugate This Caspase 7 antibody is un-conjugated
(14), (12), (9), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(250), (105), (96), (69), (37), (19), (15), (14), (8), (5), (4), (3), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-Caspase 7 Antibody

Target Details Caspase 7 Application Details Handling References for anti-Caspase 7 Antibody (ABIN783546) Images
Specificity This antibody detects Caspase-7 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Immunogen 16 amino acid peptide from near the amino-terminus of human Caspase-7

Target Details Caspase 7

Product Details anti-Caspase 7 Antibody Application Details Handling References for anti-Caspase 7 Antibody (ABIN783546) Images back to top
Antigen
Alternative Name Caspase-7 (CASP7 Antibody Abstract)
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3 (4). Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms (4). Caspase-7 activity can be directly inhibited by XIAP expression (5).Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
Gene ID 840
NCBI Accession NP_001218
UniProt P55210
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Handling References for anti-Caspase 7 Antibody (ABIN783546) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details References for anti-Caspase 7 Antibody (ABIN783546) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

References for anti-Caspase 7 Antibody (ABIN783546)

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details Handling Images back to top
Background publications

Zhivotovsky, Orrenius: "Caspase-2 function in response to DNA damage." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 859-67, 2005

Martinon, Tschopp: "Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases." in: Cell, Vol. 117, Issue 5, pp. 561-74, 2004

Wolf, Green: "Suicidal tendencies: apoptotic cell death by caspase family proteinases." in: The Journal of biological chemistry, Vol. 274, Issue 29, pp. 20049-52, 1999

Juan, McNiece, Argento, Jenkins, Gilbert, Copeland, Fletcher: "Identification and mapping of Casp7, a cysteine protease resembling CPP32 beta, interleukin-1 beta converting enzyme, and CED-3." in: Genomics, Vol. 40, Issue 1, pp. 86-93, 1997

Images

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details Handling References for anti-Caspase 7 Antibody (ABIN783546) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 7 antibody (Caspase 7, Apoptosis-Related Cysteine Peptidase) (N-Term) (ABIN783546) Immunohistochemistry of caspase-7 in rat skeletal muscle tissue with caspase-7 antibo...
Western Blotting (WB) image for anti-Caspase 7 antibody (Caspase 7, Apoptosis-Related Cysteine Peptidase) (N-Term) (ABIN783546) Western blot analysis of Caspase-7 in mouse skeletal muscle cell lysate with Caspase-...