You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) Caspase 7 antibody for Immunoprecipitation

Recommended Caspase 7 Antibody (supplied by: Log in to see )

Antigen
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) Antibodies
  • AI314680
  • CASP-7
  • CASP7
  • Caspase-7
  • caspase-7
  • caspase7
  • cmh-1
  • CMH-1
  • ICE-IAP3
  • ice-lap3
  • ICE-LAP3
  • LICE2
  • mCASP-7
  • Mch3
  • mch3
  • MCH3
  • MCH3/SCA-2
  • SCA-2
  • xCaspase-7
Epitope
active
32
28
12
7
7
6
6
6
5
5
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
241
85
61
8
7
4
4
3
3
1
Host
Rabbit
196
53
4
Clonality
Polyclonal
Conjugate
This Caspase 7 antibody is un-conjugated
12
10
7
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
205
84
76
50
27
14
12
7
6
5
4
3
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN222955
$ 430.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN127027 IHC (p) IP WB Rabbit active Log in to see Polyclonal
0.00089235755 ABIN126920 IP WB Mouse IgG1 Log in to see B4-G2
0.00089235755 ABIN222871 IP WB Mouse IgG1 Log in to see B4-G2
0.00089235755 ABIN1002039 IP IHC WB Rabbit IgG active Log in to see Polyclonal
0.00089235755 ABIN1818443 IP WB Mouse IgG2b N-Term Log in to see 4G2
0.00089235755 ABIN1002038 IP WB Mouse IgG1 Log in to see B4-G2

Top referenced anti-Caspase 7 antibody for Immunoprecipitation

Similar anti-Caspase 7 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 11 Antibodies 31 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 5 Antibodies
Immunofluorescence (IF) 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 24 Antibodies 38 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 22 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 48 Antibodies

General

Antigen Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) Antibodies
Epitope active
(32), (28), (12), (7), (7), (6), (6), (6), (5), (5), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(241), (85), (61), (8), (7), (4), (4), (3), (3), (1)
Host Rabbit
(196), (53), (4)
Clonality
Polyclonal
Conjugate This Caspase 7 antibody is un-conjugated
(12), (10), (7), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(205), (84), (76), (50), (27), (14), (12), (7), (6), (5), (4), (3), (1), (1)
Pubmed 10 references available
Supplier Log in to see

Product Details anti-Caspase 7 Antibody

Target Details Caspase 7 Application Details Handling References for anti-Caspase 7 Antibody (ABIN222955) Images
Specificity The antibody detects only the large subunit of cleaved caspase-7.
The antibody does not recognize full length of caspase-7 or other caspases.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 195 of human caspase-7
Isotype IgG

Target Details Caspase 7

Product Details anti-Caspase 7 Antibody Application Details Handling References for anti-Caspase 7 Antibody (ABIN222955) Images back to top
Antigen
Alternative Name Caspase-7 (CASP7 Antibody Abstract)
Background Caspase-7 has been identified as a major contributor to the execution of apoptosis. Caspase-7 is cleaved by many enzymes, including caspase-3, -6, -8, -9 and granzyme B. Active caspase-7 consists of a heterotetramer of two large and two small subunits. As an effector caspase, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase (PARP). The active caspase-7 antibody provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.
Synonyms: CASP7,CASP-7,ICE-LAP3,CMH-1,MCH3, EC 3.4.22.60
Gene ID 840
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Handling References for anti-Caspase 7 Antibody (ABIN222955) Images back to top
Application Notes Western blotting (0.5-4 μg/mL), Immunoprecipitation (10-20 μg/mL), and Immunohistochemistry (10-20 μg/mL).
However, the optimal concentrations should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details References for anti-Caspase 7 Antibody (ABIN222955) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) affinity purified rabbit anti-Active caspase-7 antibody in phosphate-buffered saline (PBS) containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 7 Antibody (ABIN222955)

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details Handling Images back to top
Product cited in:

Schwartz, Barker, Kaufman, Fayram, McCracken, Allen: "Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 7, pp. 3351-63, 2012

Luyer, Derikx, Beyaert, Hadfoune, van Kuppevelt, Dejong, Heineman, Buurman, Greve: "High-fat nutrition reduces hepatic damage following exposure to bacterial DNA and hemorrhagic shock." in: Journal of hepatology, Vol. 50, Issue 2, pp. 342-50, 2009

Singh, Bond, Powell, Singh, Bumpers, Grizzle, Lillard: "CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth." in: Molecular cancer therapeutics, Vol. 8, Issue 1, pp. 178-84, 2009

Nikolaev, McLaughlin, OLeary, Tessier-Lavigne: "APP binds DR6 to trigger axon pruning and neuron death via distinct caspases." in: Nature, Vol. 457, Issue 7232, pp. 981-9, 2009

Mahul-Mellier, Strappazzon, Petiot, Chatellard-Causse, Torch, Blot, Freeman, Kuhn, Garin, Verna, Fraboulet, Sadoul: "Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34954-65, 2008

Huang, Masselli, Frisch, Hunton, Jiang, Wang: "Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29401-13, 2007

Woods, Burns, Bradford, Ross, Kosyk, Swenberg, Cunningham, Rusyn: "WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 98, Issue 2, pp. 366-74, 2007

Scarabelli, Pasini, Ferrari, Ferrari, Stephanou, Lawrence, Townsend, Chen-Scarabelli, Gitti, Saravolatz, Latchman, Knight, Gardin: "Warm blood cardioplegic arrest induces mitochondrial-mediated cardiomyocyte apoptosis associated with increased urocortin expression in viable cells." in: The Journal of thoracic and cardiovascular surgery, Vol. 128, Issue 3, pp. 364-71, 2004

de Vries, Matthijsen, van Bijnen, Wolfs, Buurman: "Lysophosphatidic acid prevents renal ischemia-reperfusion injury by inhibition of apoptosis and complement activation." in: The American journal of pathology, Vol. 163, Issue 1, pp. 47-56, 2003

Scarabelli, Stephanou, Pasini, Comini, Raddino, Knight, Latchman: "Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury." in: Circulation research, Vol. 90, Issue 6, pp. 745-8, 2002

Images

Product Details anti-Caspase 7 Antibody Target Details Caspase 7 Application Details Handling References for anti-Caspase 7 Antibody (ABIN222955) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 7 antibody (Caspase 7, Apoptosis-Related Cysteine Peptidase) (active) (ABIN222955) Western blot analysis of Jurkat cells inducedwith mM of Camptothecin for hours.