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anti-Hamster Caspase 8 antibody for Immunohistochemistry

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Epitope
C-Term
42
19
18
16
15
10
10
9
9
8
7
6
6
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
350
123
98
26
21
20
3
1
Host
Rabbit
272
109
10
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
350
113
93
75
50
37
36
29
14
13
8
8
6
5
2
2
2
1
1
1
1
1
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Catalog No. ABIN1585723
$ 327.00
Plus shipping costs $45.00

Similar anti-Caspase 8 Antibodies

Application / Reactivity Human Mouse (Murine) Cow (Bovine) Rat (Rattus) Hamster Dog (Canine)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 2 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies
Simple Western (SimWes) 2 Antibodies
Western Blotting (WB) 308 Antibodies 19 Antibodies 106 Antibodies 80 Antibodies 1 Antibodies 2 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 46 Antibodies 14 Antibodies 3 Antibodies 13 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 74 Antibodies 3 Antibodies 24 Antibodies 24 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope C-Term
(42), (19), (18), (16), (15), (10), (10), (9), (9), (8), (7), (6), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
(350), (123), (98), (26), (21), (20), (3), (1)
Host Rabbit
(272), (109), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(350), (113), (93), (75), (50), (37), (36), (29), (14), (13), (8), (8), (6), (5), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Hamster, Dog (Canine), Cow (Bovine)
Purification Antibody was purified by Protein-G affinity chromatography.
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rodent Caspase-8.

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspase-8 is the most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Caspase-8 binding to the adapter molecule FADD recruits the complex to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) triggers caspase-8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. The enzyme then cleaves and activates caspase-3, caspase-4, caspase-6, caspase-7, caspase-9 and caspase-10. Granzyme B and CPP32 cleave caspase-8 at Asp 315 and Asp 330 respectively to generate the two active subunits.
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling Images back to top
Application Notes ELISA: 1:500-1:1.000, WB: 1:200-1:500, IHC: 1:200-1:500
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Preservative Sodium azide
Precaution of Use Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Handling Advice Minimize freeze-thaw cycles.
Storage -20°C
Expiry Date 12 months