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anti-Human Caspase 8 antibody for Flow Cytometry

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Epitope
AA 432-461, C-Term
47
18
17
17
13
10
10
8
8
7
7
6
6
5
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
339
96
69
18
18
14
4
1
1
1
Host
Rabbit
271
101
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
17
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
323
113
81
69
42
33
31
23
12
11
8
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN390474
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3033465 ABIN969003 FACS IHC ELISA WB Mouse IgG1 Log in to see 1H11 2
0.3033465 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11
0.3033465 ABIN2158054 FACS IF IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
0.3033465 ABIN1846137 FACS IHC ELISA WB Mouse IgG1 Log in to see
0.0010488476 ABIN189211 FACS IHC (p) IP IHC WB Rabbit IgG N-Term Log in to see E6
0.0010488476 ABIN1497105 FACS IHC ELISA WB Mouse IgG1 Log in to see 1H11
0.0010488476 ABIN207902 FACS WB Mouse IgG1 AA 217-222 Log in to see 90A992
0.0010488476 ABIN2666061 FACS Rat IgG2a Log in to see 1H10 3
0.0010488476 ABIN3023288 FACS IF IHC WB Rabbit IgG Asp391 Log in to see Polyclonal
0.0010488476 ABIN2219244 FACS IHC ELISA WB Mouse IgG1 Log in to see 13B100
0.0010488476 ABIN1841274 FACS IF IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0010488476 ABIN4288176 FACS IHC (p) WB DyLight 680 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288177 FACS IHC (p) WB DyLight 488 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288178 FACS IHC (p) WB DyLight 755 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288179 FACS IHC (p) WB PerCP Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288180 FACS IHC (p) WB PE Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288181 FACS IHC (p) WB DyLight 550 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288182 FACS IHC (p) WB DyLight 350 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288183 FACS IHC (p) WB DyLight 405 Mouse IgG1 Proform Log in to see 90A992
0.0010488476 ABIN4288184 FACS IHC (p) WB DyLight 405LS Mouse IgG1 Proform Log in to see 90A992

Top referenced anti-Caspase 8 antibody for Flow Cytometry

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Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Dot Blot (DB) 2 Antibodies
ELISA 90 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 31 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 22 Antibodies
Immunofluorescence (IF) 23 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 77 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 68 Antibodies
Immunoprecipitation (IP) 44 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope AA 432-461, C-Term
(47), (18), (17), (17), (13), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(339), (96), (69), (18), (18), (14), (4), (1), (1), (1)
Host Rabbit
(271), (101), (11), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Caspase 8 antibody is un-conjugated
(17), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(323), (113), (81), (69), (42), (33), (31), (23), (12), (11), (8), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN390474) Images
Specificity This CASP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439~469 amino acids from the C-terminal region of human CASP8.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This CASP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-461 AA from the C-terminal region of human CASP8.
Clone RB18993
Isotype Ig

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling References for anti-Caspase 8 Antibody (ABIN390474) Images back to top
Antigen
Alternative Name CASP8 (CASP8 Antibody Abstract)
Background CASP8 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases.
Synonyms: Caspase-8, CASP-8, ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, MACH, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 subunit p18, Caspase-8 subunit p1
Molecular Weight 55391 Da
Gene ID 841
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling References for anti-Caspase 8 Antibody (ABIN390474) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details References for anti-Caspase 8 Antibody (ABIN390474) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-Caspase 8 Antibody (ABIN390474)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Lin, Huang, Lin, Lin: "p-Cresol mediates autophagic cell death in renal proximal tubular cells." in: Toxicology letters, Vol. 234, Issue 1, pp. 20-9, 2015

Background publications

Ji, Gu, Hu, Wang, Liang, Xia, Lu, Song, Fu, Wang: "Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality." in: Human reproduction (Oxford, England), Vol. 24, Issue 10, pp. 2439-46, 2009

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN390474) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Western blot analysis of CASP8 antibody (C-term) (ABIN390474) in Hela cell line lysat...
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CASP8 Antibod...
Flow Cytometry (FACS) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Flow cytometric analysis of hela cells using CASP8 Antibody (C-term)(bottom histogram...