anti-Human Caspase 8 antibody for Flow Cytometry

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Epitope
AA 432-461, C-Term
43
19
18
16
15
10
10
9
9
8
7
6
6
5
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
353
118
95
25
21
20
3
2
1
Host
Rabbit
270
114
10
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
352
109
89
77
50
35
35
26
14
13
9
8
6
5
2
2
2
1
1
1
1
Options
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Catalog No. ABIN390474
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.342041 ABIN252488 CyTOF FACS IHC (p) SimWes WB Mouse IgG1 Proform Log in to see 90A992 6
13.342041 ABIN969003 FACS IHC ELISA WB Mouse IgG1 Log in to see 1H11 2
13.342041 ABIN4288173 ELISA FACS IHC IHC (p) WB Mouse IgG1 Log in to see 1H11
13.342041 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11
13.342041 ABIN1846137 FACS IHC ELISA WB Mouse IgG1 Log in to see
1 ABIN207902 FACS WB Mouse IgG1 AA 217-222 Log in to see 90A992
1 ABIN2666061 FACS Rat IgG2a Log in to see 1H10 3
1 ABIN1497105 ELISA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11
1 ABIN3023288 FACS IF IHC WB Rabbit IgG Asp391 Log in to see Polyclonal
1 ABIN4288179 FACS IHC (p) WB PerCP Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288183 FACS IHC (p) WB DyLight 405 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288182 FACS IHC (p) WB DyLight 350 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288186 FACS IHC (p) WB Alexa Fluor 488 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288163 CyTOF FACS IHC (p) SimWes WB Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288177 FACS IHC (p) WB DyLight 488 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288178 FACS IHC (p) WB DyLight 755 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288185 FACS IHC (p) WB Alexa Fluor 405 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288188 FACS IHC (p) WB Alexa Fluor 700 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288187 FACS IHC (p) WB Alexa Fluor 647 Mouse IgG1 Proform Log in to see 90A992
1 ABIN4288181 FACS IHC (p) WB DyLight 550 Mouse IgG1 Proform Log in to see 90A992

Top referenced anti-Caspase 8 antibody for Flow Cytometry

Similar anti-Caspase 8 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies
Dot Blot (DB) 2 Antibodies
ELISA 88 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 32 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 4 Antibodies
Immunocytochemistry (ICC) 26 Antibodies
Immunofluorescence (IF) 26 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 14 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 75 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 77 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope AA 432-461, C-Term
(43), (19), (18), (16), (15), (10), (10), (9), (9), (8), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(353), (118), (95), (25), (21), (20), (3), (2), (1)
Host Rabbit
(270), (114), (10), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Caspase 8 antibody is un-conjugated
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(352), (109), (89), (77), (50), (35), (35), (26), (14), (13), (9), (8), (6), (5), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN390474) Images
Specificity This CASP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439~469 amino acids from the C-terminal region of human CASP8.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This CASP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-461 AA from the C-terminal region of human CASP8.
Clone RB18993
Isotype Ig

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN390474) Images back to top
Antigen
Alternative Name CASP8 (CASP8 Antibody Abstract)
Background CASP8 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases.
Synonyms: Caspase-8, CASP-8, ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, MACH, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 subunit p18, Caspase-8 subunit p1
Molecular Weight 55391 Da
Gene ID 841
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN390474) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details ProductDetails: References for anti-Caspase 8 antibody (ABIN390474) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

ProductDetails: References for anti-Caspase 8 antibody (ABIN390474)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Lin, Huang, Lin, Lin: "p-Cresol mediates autophagic cell death in renal proximal tubular cells." in: Toxicology letters, Vol. 234, Issue 1, pp. 20-9, 2015

Background publications

Ji, Gu, Hu, Wang, Liang, Xia, Lu, Song, Fu, Wang: "Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen quality." in: Human reproduction (Oxford, England), Vol. 24, Issue 10, pp. 2439-46, 2009

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling ProductDetails: References for anti-Caspase 8 antibody (ABIN390474) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Western blot analysis of CASP8 antibody (C-term) (ABIN390474) in Hela cell line lysat...
Immunohistochemistry (IHC) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CASP8 Antibod...
Flow Cytometry (FACS) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (AA 432-461) (ABIN390474) Flow cytometric analysis of hela cells using CASP8 Antibody (C-term)(bottom histogram...