anti-Human Caspase 8 antibody for Immunofluorescence

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Epitope
C-Term
42
19
18
16
15
12
10
10
9
8
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
359
120
95
25
21
20
3
2
1
Host
Rabbit
277
115
10
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
360
109
92
78
51
36
36
27
14
13
9
8
6
5
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN615326
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.176395 ABIN2854891 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
11.176395 ABIN4288165 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
11.176395 ABIN5075507 ICC IF Rabbit IgG Log in to see Polyclonal
11.176395 ABIN4288167 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
11.176395 ABIN4288169 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN390474 FACS IF IHC (p) WB Rabbit Ig AA 432-461, C-Term Log in to see Polyclonal 2
1 ABIN252118 ICC IHC (fro) IF IHC (p) IP IHC WB Rabbit Large Subunit, Small Subunit, active Log in to see Polyclonal 33
1 ABIN4288172 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 1
1 ABIN5554665 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1871471 IF IHC WB Rabbit IgG Asp391 Log in to see Polyclonal
1 ABIN3023288 FACS IF IHC WB Rabbit IgG Asp391 Log in to see Polyclonal
1 ABIN4903139 IF IHC IP WB Mouse IgG Log in to see
1 ABIN1885811 IF IHC WB Rabbit AA 1-227 Log in to see Polyclonal
1 ABIN2219254 IF IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN4278125 ICC IF IHC IHC (fro) IHC (p) IP WB Rabbit Large Subunit, Small Subunit, active Log in to see Polyclonal
1 ABIN2880269 IF IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2219241 IC IF ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN4288166 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4288168 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2694813 IF IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Epitope C-Term
(42), (19), (18), (16), (15), (12), (10), (10), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(359), (120), (95), (25), (21), (20), (3), (2), (1)
Host Rabbit
(277), (115), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(360), (109), (92), (78), (51), (36), (36), (27), (14), (13), (9), (8), (6), (5), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling Images
Specificity This antibody reacts to Caspase 8 (CASP8).
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen CASP8 antibody was raised against synthetic peptide - KLH conjugated

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis.Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Gene ID 841
NCBI Accession NP_001073593
UniProt Q14790
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer PBS containing 0.02 % sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (C-Term) antibody (ABIN615326) Immunocytochemistry of caspase-8 in Jurkat cells with caspase-8 antibody at 2 µg/ml.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (C-Term) antibody (ABIN615326) Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (C-Term) antibody (ABIN615326) Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) (C-Term) antibody (ABIN615326) Western blot analysis of caspase-8 in Jurkat cell lysate with caspase-8 antibody at (...