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anti-Monkey Caspase 8 antibody for Western Blotting

Recommended Caspase 8 Antibody (supplied by: Log in to see )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
  • ALPS2B
  • CAP4
  • Casp-8
  • CASP-8
  • casp8
  • CASP8
  • casp8-A
  • caspase-8
  • FLICE
  • MACH
  • Mch5
  • MCH5
  • xCaspase-8
  • zgc:92075
Reactivity
Cow (Bovine), Monkey, Mouse (Murine), Rat (Rattus)
343
95
68
19
17
13
4
1
1
1
Host
Rabbit
271
104
11
2
Clonality
Polyclonal
Conjugate
This Caspase 8 antibody is un-conjugated
18
12
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
326
114
81
70
42
34
31
24
12
11
8
5
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN222878
$ 304.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13341247 ABIN969003 FACS IHC ELISA WB Mouse IgG1 Log in to see 1H11 2
0.13341247 ABIN2705692 IHC WB Rabbit pSer347 Log in to see Polyclonal
0.13341247 ABIN2705693 WB Rabbit pTyr380 Log in to see Polyclonal
0.13341247 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Log in to see 1H11
0.13341247 ABIN1846137 FACS IHC ELISA WB Mouse IgG1 Log in to see
0.0011728023 ABIN372513 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
0.0011728023 ABIN126965 WB Rabbit Log in to see Polyclonal
0.0011728023 ABIN2470495 IP IHC WB Rabbit IgG Log in to see Polyclonal
0.0011728023 ABIN1002019 WB Rabbit Log in to see Polyclonal
0.0011728023 ABIN1732676 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
0.0011728023 ABIN4288173 ELISA FACS IHC IHC (p) WB Mouse IgG1 Log in to see 1H11

Top referenced anti-Caspase 8 antibody for Western Blotting

Similar anti-Caspase 8 Antibodies

Application / Reactivity Monkey Cow (Bovine) Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 12 Antibodies 12 Antibodies 77 Antibodies 55 Antibodies
Immunoprecipitation (IP) 7 Antibodies 3 Antibodies 6 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies 5 Antibodies 17 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 6 Antibodies 5 Antibodies 31 Antibodies 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies 3 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antibodies
Reactivity Cow (Bovine), Monkey, Mouse (Murine), Rat (Rattus)
(343), (95), (68), (19), (17), (13), (4), (1), (1), (1)
Host Rabbit
(271), (104), (11), (2)
Clonality
Polyclonal
Conjugate This Caspase 8 antibody is un-conjugated
(18), (12), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(326), (114), (81), (70), (42), (34), (31), (24), (12), (11), (8), (5), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-Caspase 8 Antibody

Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN222878) Images
Blocking Peptide Blocking peptide for this product available: ABIN412656
Specificity The immunoaffinity purified antibody detects the full length (55 kDa), intermediate cleavage fragments (26-31 kDa) and cleaved large fragment (18 kDa) of caspase-8.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 392 of mouse caspase-8
Isotype IgG

Target Details Caspase 8

Product Details anti-Caspase 8 Antibody Application Details Handling References for anti-Caspase 8 Antibody (ABIN222878) Images back to top
Antigen
Alternative Name Caspase-8 (CASP8 Antibody Abstract)
Background Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro-enzyme. Activation of caspase-8 involves a two-step proteolysis: the cleavage of caspase-8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.
Synonyms: CASP8 , MGC78473 , CASP-8, MACH, procaspase-8, MCH5, ALPS2B, FLICE, CAP4, EC 3.4.22.61
Gene ID 12370
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling

Application Details

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Handling References for anti-Caspase 8 Antibody (ABIN222878) Images back to top
Application Notes Western blotting (0.5-4 μg/mL).
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details References for anti-Caspase 8 Antibody (ABIN222878) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) protein A purified rabbit anti-caspase-8 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 8 Antibody (ABIN222878)

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling Images back to top
Product cited in:

Mahul-Mellier, Strappazzon, Petiot, Chatellard-Causse, Torch, Blot, Freeman, Kuhn, Garin, Verna, Fraboulet, Sadoul: "Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34954-65, 2008

Peluffo, Stouffer, Tesone: "Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum." in: American journal of physiology. Endocrinology and metabolism, Vol. 293, Issue 5, pp. E1215-23, 2007

Woods, Burns, Bradford, Ross, Kosyk, Swenberg, Cunningham, Rusyn: "WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 98, Issue 2, pp. 366-74, 2007

Peluffo, Bussmann, Stouffer, Tesone: "Expression of caspase-2, -3, -8 and -9 proteins and enzyme activity in the corpus luteum of the rat at different stages during the natural estrous cycle." in: Reproduction (Cambridge, England), Vol. 132, Issue 3, pp. 465-75, 2006

Sasaki, Ikeda, Sato, Nakanuma: "Decreased expression of Bmi1 is closely associated with cellular senescence in small bile ducts in primary biliary cirrhosis." in: The American journal of pathology, Vol. 169, Issue 3, pp. 831-45, 2006

Images

Product Details anti-Caspase 8 Antibody Target Details Caspase 8 Application Details Handling References for anti-Caspase 8 Antibody (ABIN222878) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 8 antibody (Caspase 8, Apoptosis-Related Cysteine Peptidase) (ABIN222878) Western blot analysis of capsase-8 in Jurkat cell treated by camptothecin. Procaspase-8